ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2019
Depression and multimorbidity: Considering temporal characteristics of the associations between depression and multiple chronic diseases.
Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 6 of them syntheses that pooled it.
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Who cites it
97 citing papers in PubMed, 6 syntheses or guidelines pooled it, 162 citations in OpenAlex.
- Multimorbidity and the risk of depression: a systematic review of cohort studies.Journal of global health · 2026Pooled it
- Between Depression and Risk of Hypertension: A Systematic Review and Meta-Analysis.Brain and behavior · 2025Pooled it
- A META analysis and systematic review of the effects of exercise interventions on middle-aged and elderly patients with depression.PloS one · 2025Pooled it
- Incidence of depression among community-dwelling older adults: A systematic review.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2024Pooled it
- Prevalence of Depression and Associated Factors among Adults in Saudi Arabia: Systematic Review and Meta-Analysis (2000-2022).Depression and anxiety · 2023Pooled it
- Depression and unplanned secondary healthcare use in patients with multimorbidity: A systematic review.PloS one · 2022Pooled it
- A Cross-Nationally Validated Nomogram for Cardiometabolic Multimorbidity in Overweight/Obese Older Adults: CHARLS and HRS Cohorts.Diabetes, obesity & metabolism · 2026Article
- Well-being differences and changes in people with somatic and psychiatric disorders or multimorbidities: modelling COVID-19 as a global natural experiment of stress vulnerability.BMJ mental health · 2026Article
- The association between high-sensitivity C-reactive protein and depression symptom severity among U.S. adults: A multivariable analysis of NHANES data.Brain, behavior, & immunity - health · 2026Article
- Unraveling the psychological burden of Behçet disease: the impact of anxiety and depression on health-related quality of life outcomes.Orphanet journal of rare diseases · 2026Article
- Age-based discrimination and healthcare utilization among older adults in India: a sequential mediation model with rural-urban differences.BMC geriatrics · 2026Article
- Meals that heal: a randomized controlled trial testing the feasibility of commercial meal delivery as a convenient dietary intervention for depression.Scientific reports · 2026Article
- Lifestyle and psychosocial determinants of quality of life in Turkish community-dwelling older adults: a multivariate and hierarchical regression approach.BMC geriatrics · 2026Article
- Alleviating psychosocial distress in drug-resistant tuberculosis: a pre-post study on telephone-delivered motivational interviewing.Frontiers in public health · 2026Article
- Prediction of depressive symptoms in middle-aged and older adult hospitalized patients with chronic diseases: a multicenter study in Anhui, China using machine learning methods.Frontiers in public health · 2026Article
- Patterns of multimorbidity among low-income adults who smoke with implications for tailored interventions: a cluster analysis using a Mixture of Bernoulli model.Frontiers in medicine · 2026Article
- Multimorbidity is significantly associated with higher prevalence of depressive symptoms in middle-aged and older Chinese adults.Preventive medicine reports · 2025Article
- Prevalence, associated factors, and machine learning-based prediction of probable depression among individuals with chronic diseases in Bangladesh.BMC psychiatry · 2025Article
- Depression and incidence of inflammation-related physical health conditions: a cohort study in UK Biobank.BMC psychiatry · 2025Article
- Identifying Patterns of Depression Comorbidities Using Association Rule Learning: Insights from Maryland Medicaid Data.Healthcare informatics research · 2025Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectivesDepression frequently co-occurs with multiple chronic diseases in complex, costly, and dangerous patterns of multimorbidity. The field of health psychology may benefit from evaluating the temporal characteristics of depression's associations with common diseases, and from determining whether depression is a central connector in multimorbid disease clusters. The present review addresses these issues by focusing on 4 of the most prevalent diseases: hypertension, ischemic heart disease, arthritis, and diabetes.
methodStudy 1 assessed how prior chronic disease diagnoses were associated with current depression in a large, cross-sectional, population-based study. It assessed depression's centrality using network analysis accounting for disease prevalence. Study 2 presents a systematic scoping review evaluating the extent to which depression was prospectively associated with the onset of the 4 prevalent chronic diseases.
resultsIn Study 1 depression had the fourth highest betweenness centrality ranking of 26 network nodes and centrally connected many existing diseases and unhealthy behaviors. In Study 2 depression was associated with subsequent incidence of ischemic heart disease and diabetes across multiple meta-analyses. Insufficient information was available about depression's prospective associations with incident hypertension and arthritis.
conclusionsDepression is central in patterns of multimorbidity and is associated with incident disease for several of the most common chronic diseases, justifying the focus on screening and treatment of depression in those at risk for developing chronic disease. Future research should investigate the mediating and moderating roles of health behaviors in the association between depression and the staggered emergence over time of clusters of multimorbid chronic diseases. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.