ArticleMolecular plant pathology2019
A novel Botrytis cinerea-specific gene BcHBF1 enhances virulence of the grey mould fungus via promoting host penetration and invasive hyphal development.
Article in Molecular plant pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Arsenic Resistance Protein BcArs2 Modulates Endogenous ROS Homeostasis in Infection Cushions to Enhance the Virulence of Botrytis cinerea Toward Host Plants.Molecular plant pathology · 2026Article
- The Vacuolar CaMolecular plant pathology · 2026Article
- ApCtf1β-Interacting Target Proteins BDPH1 and BDEUL12 Regulate Pathogenicity in Arthrinium phaeospermum.Molecular plant pathology · 2026Article
- Multi-methodApplied and environmental microbiology · 2025Article
- Superhydrophobic Fatty Acid-Based Spray Coatings with Dual-Mode Antifungal Activity.ACS applied bio materials · 2025Article
- CBC Complex Regulates Hyphal Growth, Sclerotial Quantity, and Pathogenicity in the Necrotrophic FungusJournal of fungi (Basel, Switzerland) · 2025Article
- Unveiling the shield: decoding UPSIDEFrontiers in plant science · 2025Article
- Genetic and molecular landscapes of the generalist phytopathogen Botrytis cinerea.Molecular plant pathology · 2024Review
- BcTaf14 regulates growth and development, virulence, and stress responses in the phytopathogenic fungus Botrytis cinerea.Molecular plant pathology · 2023Article
- Membrane Protein Bcest Is Involved in Hyphal Growth, Virulence and Stress Tolerance ofMicroorganisms · 2023Article
- Article
- Virulence-related metabolism is activated inHorticulture research · 2022Article
- Molecular identification and characterization ofCurrent research in microbial sciences · 2021Article
- Cyclophilin BcCyp2 Regulates Infection-Related Development to Facilitate Virulence of the Gray Mold FungusInternational journal of molecular sciences · 2021Article
- Host-Induced Gene Silencing of a Multifunction GeneFrontiers in microbiology · 2021Article
- Clathrin Is Important for Virulence Factors Delivery in the Necrotrophic FungusFrontiers in plant science · 2021Article
- The Destructive Fungal PathogenPathogens (Basel, Switzerland) · 2020Review
- Two mating-type genes MAT1-1-1 and MAT1-1-2 with significant functions in conidiation, stress response, sexual development, and pathogenicity of rice false smut fungus Villosiclava virens.Current genetics · 2020Article
- Transcriptome analysis and functional validation reveal a novel gene, BcCGF1, that enhances fungal virulence by promoting infection-related development and host penetration.Molecular plant pathology · 2020Article
- BcRPD3-Mediated Histone Deacetylation Is Involved in Growth and Pathogenicity ofFrontiers in microbiology · 2020Article
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10 authors.
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Abstract
Botrytis cinerea is the causative agent of grey mould on over 1000 plant species and annually causes enormous economic losses worldwide. However, the fungal factors that mediate pathogenesis of the pathogen remain largely unknown. Here, we demonstrate that a novel B. cinerea-specific pathogenicity-associated factor BcHBF1 (hyphal branching-related factor 1), identified from virulence-attenuated mutant M8008 from a B. cinerea T-DNA insertion mutant library, plays an important role in hyphal branching, infection structure formation, sclerotial formation and full virulence of the pathogen. Deletion of BcHBF1 in B. cinerea did not impair radial growth of mycelia, conidiation, conidial germination, osmotic- and oxidative-stress adaptation, as well as cell wall integrity of the ∆Bchbf1 mutant strains. However, loss of BcHBF1 impaired the capability of hyphal branching, appressorium and infection cushion formation, appressorium host penetration and virulence of the pathogen. Moreover, disruption of BcHBF1 altered conidial morphology and dramatically impaired sclerotial formation of the mutant strains. Complementation of BcHBF1 completely rescued all the phenotypic defects of the ∆Bchbf1 mutants. During young hyphal branching, host penetration and early invasive growth of the pathogen, BcHBF1 expression was up-regulated, suggesting that BcHBF1 is required for these processes. Our findings provide novel insights into the fungal factor mediating pathogenesis of the grey mould fungus via regulation of its infection structure formation, host penetration and invasive hyphal branching and growth.
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