Evidence map›Paper›PMID 31008365›Full record

ArticleEndocrinology, diabetes & metabolism2019

Occurrence of severe hypoglycaemic events among US youth and young adults with type 1 or type 2 diabetes.

Sharon Saydah, Giuseppina Imperatore, Jasmin Divers, Ronny Bell, Leora Henkin, Elizabeth Mayer-Davis, Victor W Zhong, Dana Dabelea, Jean M Lawrence, Catherine Pihoker

Open access · goldAbstract read
In one paragraph

Article in Endocrinology, diabetes & metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Sharon SaydahDivision of Diabetes Translation, Centers for Disease Control and Prevention National Center for Chronic Disease Prevention and Health Promotion Atlanta Georgia.ORCID https://orcid.org/0000-0002-6350-5300
Giuseppina ImperatoreDivision of Diabetes Translation, Centers for Disease Control and Prevention National Center for Chronic Disease Prevention and Health Promotion Atlanta Georgia.
Jasmin DiversDepartment of Biostatistics Wake Forest School of Medicine Wake Forest North Carolina.
Ronny BellDepartment of Public Health, Brody School of Medicine East Carolina University Greenville North Carolina.
Leora HenkinDepartment of Biostatistics Wake Forest School of Medicine Wake Forest North Carolina.
Elizabeth Mayer-DavisDepartments of Nutrition and Medicine University of North Carolina at Chapel Hill Chapel Hill North Carolina.ORCID https://orcid.org/0000-0003-3858-0517
Victor W ZhongDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Evanston Illinois.
Dana DabeleaDepartments of Epidemiology and Pediatrics University of Colorado Anschutz Medical Campus Aurora Colorado.ORCID https://orcid.org/0000-0001-9514-8929
Jean M LawrenceDepartment of Research & Evaluation Kaiser Permanente Southern California Pasadena California.
Catherine PihokerDepartment of Pediatrics University of Washington Seattle Washington.ORCID https://orcid.org/0000-0001-9074-7770
Centers for Disease Control and Prevention · USWake Forest University · USEast Carolina University · USKaiser Permanente · USNorthwestern University · USUniversity of Colorado Anschutz Medical Campus · USUniversity of North Carolina at Chapel Hill · USUniversity of Washington · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4)SEARCH for Diabetes in Youth Cohort StudyUC4DK108173 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DAGOSTINO, RALPH B. · 2015 to 2016
$14.8M
HSRD VA HIR 10-001NCCDPHP CDC HHS U01 DP000247NCCDPHP CDC HHS U18 DP002708NCCDPHP CDC HHS U18 DP002709NCCDPHP CDC HHS U18 DP002710NCCDPHP CDC HHS U18 DP002714NCCDPHP CDC HHS U18 DP006138NCCDPHP CDC HHS U18 DP006139NIDDK NIH HHS P30 DK017047NIDDK NIH HHS UC4 DK108173
6 · The paper itself

Abstract

objectiveAlthough severe hypoglycaemia (SH) can lead to adverse health outcomes, little is known about its occurrence and re-occurrence among youth with type 1 or type 2 diabetes.

methodsThis study included 2740 participants aged <20 years at diabetes diagnosis and 5-14 years diabetes duration from the SEARCH for Diabetes in Youth Cohort Study. Participants reported SH events in the past 6 months. Differences in SH events by demographic and clinical factors were tested using logistic regression models.

resultsSevere hypoglycaemia in the past 6 months was more common among youth with type 1 (7.0%, 168 of 2399) than with type 2 diabetes (2.6%, nine of 341) (

conclusionsIn youth with diabetes, SH was common even within a short 6-month window. Better understanding the causes of SH may help prevent them from occurring.

Indexed as

hypoglycaemic eventstype 1 diabetestype 2 diabetesyouth

Identifiers

PMID31008365
PMCPMC6458461
OpenAlexW2909930503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.