Evidence map›Paper›PMID 31008348›Full record

ArticleEuropean stroke journal2018

In-hospital dynamics of glucose, blood pressure and temperature predict outcome in patients with acute ischaemic stroke.

Anastasia Skafida, Asimina Mitrakou, Georgios Georgiopoulos, Maria Alevizaki, Konstantinos Spengos, Konstantinos Takis, George Ntaios, Christos Thomadakis, Konstantinos Vemmos

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in European stroke journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Anastasia SkafidaDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens Medical School, Alexandra Hospital, Athens, Greece.
Asimina MitrakouDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens Medical School, Alexandra Hospital, Athens, Greece.
Georgios GeorgiopoulosDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens Medical School, Alexandra Hospital, Athens, Greece.
Maria AlevizakiDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens Medical School, Alexandra Hospital, Athens, Greece.
Konstantinos SpengosDepartment of Neurology, National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens, Greece.
Konstantinos TakisDepartment of Neurology, Mediteraneo Hospital, Athens, Greece.
George Ntaios5Department of Medicine, University of Thessaly, Larissa, Greece.
Christos ThomadakisDepartment of Hygiene and Epidemiology, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos VemmosDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens Medical School, Alexandra Hospital, Athens, Greece.
Alexandra Hospital · GRNational and Kapodistrian University of Athens · GREginition Hospital · GRGeneral Hospital of Athens G. Genimatas · GRJupiter Medical Center · USUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed to assess alterations in glucose, blood pressure and temperature in acute ischaemic stroke and investigate their association with early all-cause mortality and functional outcome. PATIENTS AND

methodsWe studied all consecutive acute ischaemic stroke patients admitted in 2001-2010 to the Acute Stroke Unit, at Alexandra University Hospital, in Athens. Serial measurements were performed in the first seven days post-stroke and different parameters have been estimated: mean daily values, variability, subject-specific baseline levels and rate of change in serial measurements. Cox-proportional-hazards-model analysis and logistic-regression analysis were applied to investigate the association between these parameters and all-cause mortality and functional outcome after adjustment for known confounders of stroke outcome.

resultsIn 1271 patients (mean age 72.3 ± 11.2 years), after adjusting for confounders, baseline glucose levels (HR: 1.005, 95%CI: 1.001-1.01; DISCUSSION: The main strength of our study is that we analysed simultaneously three parameters and we used four different variables for each parameter of interest.

conclusionBaseline glucose levels, variability of SBP and baseline temperature and its rate of change are independent predictors of all-cause mortality. Baseline values of temperature and the rate of changes in SBP and temperature are independent predictors of poor functional outcome.

Indexed as

Acute strokeblood pressurehyperglycaemiamortalitytemperature

Identifiers

PMID31008348
PMCPMC6460405
OpenAlexW2793385288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.