ArticleEuropean stroke journal2018
European Stroke Organisation (ESO) guidelines on glycaemia management in acute stroke.
Article in European stroke journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization.International journal of stroke : official journal of the International Stroke Society · 2023Pooled it
- Response to Middleton et al.European stroke journal · 2026Article
- Hypoxia-inducible factor-1: A new neuroprotective agent for the treatment of hyperglycemia after stroke.Neural regeneration research · 2026Article
- Malignant Cerebral Edema after Large-Core Anterior Circulation Stroke in the Thrombectomy Era: Prediction and Neurocritical Care Pathways.Neurocritical care · 2026Review
- Continuous glucose monitoring and glycaemic variability in acute ischaemic stroke: a systematic review with narrative synthesis.Acta diabetologica · 2026Review
- Re: Stroke Action Plan for Europe 2018-2030 (SAP-E): mid-term review and update.European stroke journal · 2026Article
- Effect of glucose on functional outcome and case-fatality in patients with spontaneous intracerebral hemorrhage.BMC neurology · 2026Article
- Stroke Action Plan for Europe 2018-2030 (SAP-E): mid-term review and update.European stroke journal · 2026Review
- Day-of-surgery quality gaps in glycemic management: a retrospective cohort study.Perioperative medicine (London, England) · 2025Article
- Stress-Induced Hyperglycemia Predicts Poor Outcomes in Primary Intracerebral Hemorrhage Patients.NeuroSci · 2025Article
- [Recent clinical studies and the S3 guidelines on stroke].Radiologie (Heidelberg, Germany) · 2025Review
- Impact of glycemic treatment and blood glucose monitoring on outcomes in patients with acute ischemic stroke without prior diabetes: a longitudinal cohort study.Diabetology & metabolic syndrome · 2024Article
- [Glycemic management in the stroke unit and its relationship with morbidity and mortality].Revista de neurologia · 2024Observational
- Article
- Post-Ischemic Stroke Cardiovascular Risk Prevention and Management.Healthcare (Basel, Switzerland) · 2024Review
- Glycemic variability after mechanical thrombectomy for anterior circulation acute ischemic stroke.Revista de neurologia · 2024Article
- Systemic inflammation and Oxidative stress with stroke mortality among patients admitted in tertiary Hospital in Uganda: a prospective cohort study in southwestern Uganda.Research square · 2024Article
- Predictive factors for early neurological deterioration after intravenous thrombolysis of single subcortical infarction in the territory of the middle cerebral artery.Brain and behavior · 2023Article
- Translation of nurse-initiated protocols to manage fever, hyperglycaemia and swallowing following stroke across Europe (QASC Europe): A pre-test/post-test implementation study.European stroke journal · 2023Article
- The Prognostic Significance of Early Glycemic Profile in Acute Ischemic Stroke Depends on Stroke Subtype.Journal of clinical medicine · 2023Article
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Authors and funding
7 authors.
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Abstract
backgroundHyperglycaemia is a frequent complication in acute stroke that has been shown to be independently associated with larger infarct size, haematoma growth, poor clinical outcome and mortality. This Guideline Document presents the European Stroke Organisation (ESO) Guidelines for the management of blood glucose levels in patients with acute ischemic or haemorrhagic stroke.
methodsThe working group identified related questions and developed its recommendations based on evidence from randomised controlled trials following the standard operating procedure of the ESO. This Guideline Document was reviewed and approved by the European Stroke Organisation Guidelines Committee and the European Stroke Organisation Executive Committee.
resultsWe found low-quality evidence from clinical trials in ischemic or haemorrhagic stroke exploring the use of intravenous insulin aimed to achieve a tight glycaemic control with different glucose level targets and several other sources of heterogeneity. None of these trials neither the meta-analysis of them have demonstrated any significant benefit of tight glycaemic control with intravenous insulin in acute ischemic or haemorrhagic stroke patients on functional outcome or in survival and they have shown an increased risk for hypoglycaemia.
conclusionsWe suggest against the routine use of tight glycaemic control with intravenous insulin as a means to improve outcomes. The currently available data about the management of glycaemia in patients with acute stroke are limited and the strengths of the recommendations are therefore weak. Nevertheless, this does not prevent that hyperglycaemia in acute stroke patients could be treated as any other hospitalised patient.
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