ArticleEuropean stroke journal2016
Gender and hormonal influences in reversible cerebral vasoconstriction syndrome.
Article in European stroke journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 43 citations in OpenAlex.
- Ejaculation-Triggered Reversible Cerebral Vasoconstriction Syndrome: A Case Report with Longitudinal Neuroimaging.Diagnostics (Basel, Switzerland) · 2026Article
- A postpartum woman with recurrent headaches and transient neurological deficits: a case report.Journal of medical case reports · 2026Article
- Review
- Concurrent Reversible Cerebral Vasoconstriction Syndrome and Bilateral Vertebral Artery Dissection in the Postpartum Period: A Case Report.Clinical case reports · 2026Article
- Spinal cord reversible cerebral vasoconstriction syndrome.Proceedings (Baylor University. Medical Center) · 2025Article
- Posterior reversible enzephalopathie syndrome (PRES) following vestibular schwannoma surgery - Case report and review of the current theories on pathophysiology of PRES.Brain & spine · 2025Review
- Treatment-Related Reversible Cerebral Vasoconstriction Syndrome.Journal of clinical medicine · 2024Review
- Headache Attributed to Reversible Cerebral Vasoconstriction Syndrome (RCVS).Diagnostics (Basel, Switzerland) · 2023Review
- Complications of reversible cerebral vasoconstriction syndrome in relation to age.Journal of neurology · 2023Article
- Neurological Complications in Pregnancy and the Puerperium: Methodology for a Clinical Diagnosis.Journal of clinical medicine · 2023Review
- Pathophysiology of reversible cerebral vasoconstriction syndrome.Journal of biomedical science · 2022Review
- Inactivated COVID-19 vaccine induced acute stroke-like focal neurologic symptoms: a case series.BMC neurology · 2022Article
- Reversible Cerebral Vasoconstriction Syndrome in the Postpartum Period: A Systematic Review and Meta-Analysis.Neurology international · 2022Review
- Hemorrhagic reversible cerebral vasoconstriction syndrome: A retrospective observational study.Journal of neurology · 2021Observational
- Cerebrovascular disease in women.Therapeutic advances in neurological disorders · 2021Review
- Grief-induced reversible cerebral vasoconstriction syndrome (RCVS).BMJ case reports · 2020Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe reversible cerebral vasoconstriction syndromes, including postpartum angiopathy, have been characterized over the last decade. Women are predominantly affected. Some studies suggest that postpartum angiopathy carries a worse prognosis. PATIENTS AND
methodsWe compared the clinical, neuroimaging, and angiographic features of 36 men, 110 non-pregnant women and 16 postpartum women included in our single-center cohort of patients with reversible cerebral vasoconstriction syndromes encountered from 1998 to 2016.
resultsAs compared to men, non-pregnant women were older (48 ± 11 vs. 34 ± 13 years, p < 0.001), had more underlying migraine (49% vs. 19%, p = 0.002), depression (53% vs. 14%, p < 0.001) and serotonergic antidepressant use (45% vs. 11%, p < 0.001), developed more clinical worsening (18% vs. 3%, p = 0.022), more infarcts (39% vs. 20%, p = 0.031) and worse angiographic severity scores (23 ± 14 vs. 10.9 ± 10.3, p < 0.001), but had similar discharge outcomes (modified Rankin scale scores 0-3, 90% vs. 91%, p = 0.768). Sexual activity was an important trigger in men (22% vs. 4%, p = 0.002). As compared to non-pregnant women, postpartum angiopathy patients were younger (33 ± 6 years, p < 0.001) and had less vasoconstrictive drug exposure (25% vs. 67%, p = 0.002) but showed similar clinical, radiological and angiographic findings and similar discharge outcomes (modified Rankin scale scores 0-3 in 94%, p = 0.633). There were no significant differences between pre- and post-menopausal women, or those with and without hysterectomy. DISCUSSION/
conclusionThe observed gender differences in reversible cerebral vasoconstriction syndromes may result from hormonal or non-hormonal factors. Hormonal imbalances may trigger reversible cerebral vasoconstriction syndromes. Given the absence of significant differences in the female subgroups, hormonal factors do not appear to significantly affect the course or outcome of reversible cerebral vasoconstriction syndromes.
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