ReviewEuropean stroke journal2016
Ischemic stroke in the young: Current perspectives on incidence, risk factors, and cardiovascular prognosis.
Review in European stroke journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Cognitive impairment after a stroke in young adults: A systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2023Pooled it
- Reminiscence therapy-based care program relieves post-stroke cognitive impairment, anxiety, and depression in acute ischemic stroke patients: a randomized, controlled study.Irish journal of medical science · 2021Trial
- Article
- Time Lost Is Brain Lost: Insights into Acute Ischaemic Stroke Delays in a Tertiary Care Super-speciality Centre in Jharkhand.Annals of neurosciences · 2026Article
- Stroke risk factors and outcomes in Trinidad and Tobago: the START study.BMC neurology · 2026Observational
- Ischaemic stroke in young adults: an overview of the classification, risk factors, aetiologies and outcomes.Singapore medical journal · 2026Review
- Hypertension as the Leading Cause of Stroke in Young Adults in a Northern Nigerian Hospital: A Retrospective Study.Cureus · 2026Article
- Experiences of young adults with cardiovascular disease in using digital health: a protocol for a qualitative systematic review and meta-synthesis from the perspective of media affordances.Frontiers in cardiovascular medicine · 2026Article
- Nationwide Trends in Incidence of Stroke and Transient Ischemic Attack in Younger and Older Adults in Norway 2001 to 2021.Journal of the American Heart Association · 2025Article
- Association of Subgingival Microbiota Composition With Risk, Severity, and Outcome of Cryptogenic Ischemic Stroke in Young Adults.Journal of the American Heart Association · 2025Observational
- Article
- Pulmonary Embolism in Acute Ischaemic Stroke: Evolving Evidence, Diagnostic Challenges, and a Novel Thromboinflammatory Axis Hypothesis.International journal of molecular sciences · 2025Review
- Management of cervical artery dissection: new evidence and future directions.Journal of neurology · 2025Review
- Stroke in young adults in the Middle East and North Africa region: What is the difference from elsewhere? A report from sixteen centers experiences.Frontiers in neurology · 2025Article
- Trends, risk profiles, and outcomes of ischemic stroke in young adults: a population-based analysis using the national inpatient sample (2010-2022).Frontiers in neurology · 2025Article
- How to return? experiences of patients in working age after first Ischaemic stroke: an interpretative phenomenological analysis of patient´s perspective at 12 - 24 months post-stroke.International journal of qualitative studies on health and well-being · 2024Observational
- Predicting 3-month poor functional outcomes of acute ischemic stroke in young patients using machine learning.European journal of medical research · 2024Article
- Ischemic Stroke in Young Tunisian Adults.La Tunisie medicale · 2024Article
- Testosterone supplementation and stroke in young adults: a review of the literature.Frontiers in neurology · 2024Review
- Effect of the Frequency of Rehabilitation Treatments on the Long-Term Mortality of Stroke Survivors with Mild-to-Moderate Disabilities under the Korean National Health Insurance Service System.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
About one-fourth of ischemic strokes occur in working-aged individuals in the high-income countries, with worldwide increasing incidence in this age group from 1980s to present. Recent evidence suggests that traditional vascular risk factors are more prevalent than previously suggested in young adult stroke patients and they accumulate with age particularly in men. Accordingly, relatively high rates of atherosclerotic changes have been detected in these patients. The strength of association of vascular risk factors has gone poorly studied, however. Many young patients with ischemic stroke have, in turn, no traditional risk factors, while they may harbor other conditions with weak or uncertain association with the stroke alone. These individual conditions often represent a risk factor that may be strictly young-age specific, more prevalent in younger than older stroke patients (e.g. patent foramen ovale), or more prevalent among the young in the population. Despite high rates of vascular risk factors and atherosclerotic changes, these findings do not translate to higher frequencies of identified classical stroke mechanisms. In fact, cryptogenic causes are markedly common and even more frequent among the very young patients. Limited randomized trial evidence exists to support secondary prevention decision-making in patients, yet they face an increased risk of death and future vascular events for years to come-dependent on risk factor profile and cause of the stroke. This review provides an overview of recent data on epidemiology, risk factors, and their strength of association in ischemic stroke in the young. Furthermore, the relationship between with the risk factors and cardiovascular outcomes and key features on the evidence related to secondary prevention will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.