Evidence map›Paper›PMID 31008116›Full record

ArticleJournal of immunology research2019

Ovarian Cancer Stem Cells with High ROR1 Expression Serve as a New Prophylactic Vaccine for Ovarian Cancer.

Di Wu, Xiaoyu Yu, Jing Wang, Xu Hui, Yunxia Zhang, Yunlang Cai, Mulan Ren, Mei Guo, Fengshu Zhao, Jun Dou

Abstract read
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  8. Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1).Acta crystallographica. Section F, Structural biology communications · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Di Wu *Department of Pathogenic Biology and Immunology of Medical School, Southeast University, Nanjing 210009, China.ORCID 0000-0002-5151-6010
Xiaoyu Yu *Department of Pathogenic Biology and Immunology of Medical School, Southeast University, Nanjing 210009, China.
Jing Wang *Department of Gynecology & Obstetrics, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, China.
Xu HuiDepartment of Pathogenic Biology and Immunology of Medical School, Southeast University, Nanjing 210009, China.ORCID 0000-0002-2888-1490
Yunxia ZhangDepartment of Pathogenic Biology and Immunology of Medical School, Southeast University, Nanjing 210009, China.
Yunlang CaiDepartment of Gynecology & Obstetrics, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, China.
Mulan RenDepartment of Gynecology & Obstetrics, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, China.
Mei GuoDepartment of Pathogenic Biology and Immunology of Medical School, Southeast University, Nanjing 210009, China.ORCID 0000-0002-8653-8180
Fengshu ZhaoDepartment of Pathogenic Biology and Immunology of Medical School, Southeast University, Nanjing 210009, China.ORCID 0000-0002-9722-0055
Jun DouDepartment of Pathogenic Biology and Immunology of Medical School, Southeast University, Nanjing 210009, China.ORCID 0000-0001-6944-5874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor vaccines offer a number of advantages for cancer treatment. In the study, the vaccination with cancer stem cells (CSCs) with high expression of the type I receptor tyrosine kinase-like orphan receptor (ROR1) was evaluated in a murine model for the vaccine's immunogenicity and protective efficacy against epithelial ovarian carcinoma (EOC). CD117

Indexed as

AnimalsCancer VaccinesCarcinoma, Ovarian EpithelialCell Line, TumorFemaleHumansImmunogenicity, VaccineMiceMice, Inbred BALB CMice, Inbred C57BLNeoplastic Stem CellsOvarian NeoplasmsReceptor Tyrosine Kinase-like Orphan ReceptorsVaccinationCancer VaccinesReceptor Tyrosine Kinase-like Orphan ReceptorsRor1 protein, mouse

Identifiers

PMID31008116
PMCPMC6441513

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.