ArticleJournal of diabetes research2019
Adaptive Optics (rtx1) High-Resolution Imaging of Photoreceptors and Retinal Arteries in Patients with Diabetic Retinopathy.
Article in Journal of diabetes research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 60 citations in OpenAlex.
- The positive correlation between the progressive photoreceptor damage and the increased macular leakage indicating the severity of diabetic retinopathy.Journal of diabetes investigation · 2026Article
- Advances in diagnosing and treating diabetic retinopathy.Nature reviews. Endocrinology · 2026Review
- Multimodal imaging of photoreceptor and vascular changes in lamellar macular hole and epiretinal membrane-associated foveoschisis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Adaptive Optics RTX1 Imaging for Early Detection of Retinal Vascular Remodeling in Hypertensive Retinopathy: A Review.Journal of clinical medicine · 2026Review
- Robust spatial phase prediction from paired intensities using multi-scale wavelets and aberration sensing network.Biomedical optics express · 2026Article
- Ophthalmological Microvascular Changes in ANOCA/INOCA Disease and Ophthalmological Methods to Detect Them-A Systematic Review.Journal of clinical medicine · 2026Review
- How early can we detect diabetic retinopathy? A narrative review of imaging tools for structural assessment of the retina.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- Dynamics of color vision recovery in Vogt-Koyanagi-Harada disease: a longitudinal study using cone contrast test and adaptive optics imaging.Journal of ophthalmic inflammation and infection · 2025Article
- Assessment of Microvascular Disturbances in Children with Type 1 Diabetes-A Pilot Study.Biosensors · 2025Article
- Multimodal Imaging of Diabetic Retinopathy: Insights from Optical Coherence Tomography Angiography and Adaptive Optics.Diagnostics (Basel, Switzerland) · 2025Article
- Endothelial Glycocalyx Anomalies and Ocular Manifestations in Patients with Post-Acute COVID-19.Journal of clinical medicine · 2024Article
- Photoreceptor Characteristics in Diabetic Retinopathy vs Controls Using Adaptive Optics Imaging: Systematic Review.Journal of vitreoretinal diseases · 2024Review
- Macular vascular and photoreceptor changes for diabetic macular edema at early stage.Scientific reports · 2024Article
- Early remodeling and loss of light-induced dilation of retinal small arteries in CADASIL.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- High-Resolution Imaging of Cones and Retinal Arteries in Patients with Diabetes Mellitus Type 1 Using Adaptive Optics (rtx1).Biomedicines · 2024Article
- The effect of Orem self-care model on the improvement of symptoms and quality of life in patients with diabetes: A scoping review.Investigacion y educacion en enfermeria · 2024Article
- Is Primary Open-Angle Glaucoma a Vascular Disease? Assessment of the Relationship between Retinal Arteriolar Morphology and Glaucoma Severity Using Adaptive Optics.Journal of clinical medicine · 2024Article
- Defining reference values of arterioles in healthy individuals for studies with adaptive optics imaging.Frontiers in ophthalmology · 2024Article
- Clinical Application of Adaptive Optics Imaging in Diagnosis, Management, and Monitoring of Ophthalmological Diseases: A Narrative Review.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
- Adaptive vessel tracing and segmentation in OCT enables the robust detection of wall-to-lumen ratio abnormalities in 5xFAD mice.Biomedical optics express · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetic retinopathy (DR) is the leading cause of impaired vision in patients with diabetes mellitus. An adaptive optics retinal camera (rtx1™; Imagine Eyes, France) was used to capture images of cones and retinal arteries from patients with DR.
objectiveCone parameters (density, interphotoreceptor distance, and regularity) and retinal artery parameters (wall thickness, lumen diameter, WLR, and WCSA) were analyzed in 36 patients with nonproliferative DR (NPDR; 22 with mild NPDR and 14 with moderate NPDR) and in 20 healthy volunteers (the control group).
resultsCone density at 2° eccentricities was significantly lower in the DR compared to the control group (19822 ± 4342 cells/mm
conclusionsDecreased cone regularity and density are seen in patients with mild and moderate NPDR. Abnormalities of retinal arterioles show signs of arteriolar dysfunction in DR. Retinal image analysis with the rtx1 offers a novel noninvasive measurement of early changes in the neural cells and retina vasculature in diabetic eyes.
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