Evidence map›Paper›PMID 31008030›Full record

ArticleJournal of cardiovascular echography

Left Atrial Volume during Stress Is Associated with Increased Risk of Arrhythmias in Patients with Hypertrophic Cardiomyopathy.

Giuseppe Limongelli, Vincenzo Fioretti, Marco Di Maio, Marina Verrengia, Marta Rubino, Rita Gravino, Daniele Masarone, Antonello D'Andrea, Quirino Ciampi, Eugenio Picano and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiovascular echography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. The Impact of Mavacamten on the Pathophysiology of Hypertrophic Cardiomyopathy: A Narrative Review.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2022
    Review
  4. Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Giuseppe LimongelliCardiomyopathies and Heart Failure Department, Monaldi Hospital, Università della Campania "Luigi Vanvitelli," Nocera Inferiore, Italy.
Vincenzo FiorettiCardiomyopathies and Heart Failure Department, Monaldi Hospital, Università della Campania "Luigi Vanvitelli," Nocera Inferiore, Italy.
Marco Di MaioCardiomyopathies and Heart Failure Department, Monaldi Hospital, Università della Campania "Luigi Vanvitelli," Nocera Inferiore, Italy.
Marina VerrengiaCardiomyopathies and Heart Failure Department, Monaldi Hospital, Università della Campania "Luigi Vanvitelli," Nocera Inferiore, Italy.
Marta RubinoCardiomyopathies and Heart Failure Department, Monaldi Hospital, Università della Campania "Luigi Vanvitelli," Nocera Inferiore, Italy.
Rita GravinoCardiomyopathies and Heart Failure Department, Monaldi Hospital, Università della Campania "Luigi Vanvitelli," Nocera Inferiore, Italy.
Daniele MasaroneCardiomyopathies and Heart Failure Department, Monaldi Hospital, Università della Campania "Luigi Vanvitelli," Nocera Inferiore, Italy.
Antonello D'AndreaCardiology Unit, Umberto I Hospital, Nocera Inferiore, Italy.
Quirino CiampiCardiology Department, Ospedale Fatebenefratelli, Benevento, Italy.
Eugenio PicanoCNR Institute of Clinical Physiology, Pisa, Italy.
Perry ElliottInherited Cardiovascular Disease Unit, Institute of Cardiovascular Sciences, University College of London, London, UK.
Giuseppe PacileoCardiomyopathies and Heart Failure Department, Monaldi Hospital, Università della Campania "Luigi Vanvitelli," Nocera Inferiore, Italy.
Ospedale Monaldi · ITUniversity College London · GBUniversity of Campania "Luigi Vanvitelli" · ITIstituto di Fisiologia Clinica · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn patients affected by hypertrophic cardiomyopathy (HCM), left atrial volume index (LAVi) is associated with an increased risk of tachyarrhythmias and major clinical events. To date, the clinical meaning of LAVi measured during exercise (stress LAVi [sLAVi]) has not yet been investigated in HCM. This study sought to evaluate the correlation between LAVi/sLAVi and clinical outcome (risk of arrhythmias and heart failure [HF]) in patients with HCM. METHODS AND

resultsWe enrolled a total of 51 consecutive patients with HCM (39 men; mean age: 39.41 ± 17.9 years) who underwent standard and stress echocardiography, following a common protocol. During follow-up (median follow-up was 1.82 years), the following composite endpoints were collected: ARRHYT endpoint (atrial fibrillation, paroxysmal supraventricular tachycardia, nonsustained ventricular tachycardia (VT), sustained VT, ventricular fibrillation, syncope of likely cardiogenic nature, and sudden cardiac death) and HF endpoint (worsening of functional class and left ventricular ejection fraction, hospitalization, and death for end-stage HF). Eight patients were lost at follow-up. ARRHYT endpoint occurred in 13 (30.2%) patients (8, 18.6%, supraventricular and 10, 23.2%, ventricular arrhythmias), whereas HF endpoint occurred in 5 (11.6%) patients. sLAVi (mean value of 31.16 ± 10.15 mL/m

conclusionThese findings encourage future studies on sLAVi, as a potential predictor of arrhythmias and adverse outcome in patients with HCM.

Indexed as

Hypertrophic cardiomyopathyleft atrial volumestress echocardiography

Identifiers

PMID31008030
PMCPMC6450231
OpenAlexW2924439872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.