Evidence map›Paper›PMID 31007967›Full record

ArticleACS catalysis2019

Development of an Improved System for the Carboxylation of Aryl Halides through Mechanistic Studies.

David J Charboneau, Gary W Brudvig, Nilay Hazari, Hannah M C Lant, Andrew K Saydjari

Abstract read
In one paragraph

Article in ACS catalysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Organic process research & development · 2026
    Article
  3. Discovery of NiJournal of the American Chemical Society · 2025
    Article
  4. Article
  5. Article
  6. COTopics in current chemistry (Cham) · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Ligand and solvent effects on COChemical science · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David J CharboneauDepartment of Chemistry, Yale University, P.O. Box 208107, New Haven, Connecticut 06520, United States.
Gary W BrudvigDepartment of Chemistry, Yale University, P.O. Box 208107, New Haven, Connecticut 06520, United States.ORCID 0000-0002-7040-1892
Nilay HazariDepartment of Chemistry, Yale University, P.O. Box 208107, New Haven, Connecticut 06520, United States.ORCID 0000-0001-8337-198X
Hannah M C LantDepartment of Chemistry, Yale University, P.O. Box 208107, New Haven, Connecticut 06520, United States.
Andrew K SaydjariDepartment of Chemistry, Yale University, P.O. Box 208107, New Haven, Connecticut 06520, United States.

Funding

Mechanistic Studies to Rationally Design Ni and Pd Catalysts for Cross-CouplingR01GM120162 · NIGMS · YALE UNIVERSITY · PI HAZARI, NILAY · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM120162
6 · The paper itself

Abstract

The nickel-catalyzed carboxylation of organic halides or pseudohalides using carbon dioxide is an emerging method to prepare synthetically valuable carboxylic acids. Here, we report a detailed mechanistic investigation of these reactions using the carboxylation of aryl halides with (PPh

Indexed as

carbon dioxidecatalysiscross-electrophile couplinghomogeneous organic reductantmechanismnickel

Identifiers

PMID31007967
PMCPMC6469866

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.