Evidence map›Paper›PMID 31007904›Full record

ArticleRSC advances2015

Silver(I) ions modulate the stability of DNA duplexes containing cytosine, methylcytosine and hydroxymethylcytosine at different salt concentrations.

Yong Wang, Brandon Ritzo, Li-Qun Gu

Open access · greenAbstract read
In one paragraph

Article in RSC advances, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yong WangDepartment of Biological Engineering, University of Missouri, 134 research park, Columbia, MO 65211, USA. wayong@missouri.edu; Tel: +1 573 8822086.
Brandon RitzoDepartment of Biological Engineering, University of Missouri, 134 research park, Columbia, MO 65211, USA. wayong@missouri.edu; Tel: +1 573 8822086.
Li-Qun GuDepartment of Biological Engineering, University of Missouri, 134 research park, Columbia, MO 65211, USA. wayong@missouri.edu; Tel: +1 573 8822086.
University of Missouri · US

Funding

Programmable Multi-Target Detection Using an Aptamer-Integrated NanoporeR01GM079613 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI GU, LI-QUN (ANDREW) · 2007 to 2011
$1.3M
Nanopore single-molecule dielectrophoresis and biomedical detectionR01GM114204 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI GU, LI-QUN (ANDREW) · 2015 to 2017
$887k
NIGMS NIH HHS R01 GM079613NIGMS NIH HHS R01 GM114204
6 · The paper itself

Abstract

Silver(I) ions can stabilize cytosine-cytosine, cytosine (C)-methylcytosine (5mC) and cytosine-hydroxymethylcytosine (5hmC) mismatched-base pairs. While cytosine modifications regulate DNA stability to regulate cellular functions, silver ions can modulate the stability of C-C, C-5mC and C-5hmC containing DNA duplexes in a salt concentration dependent manner.

Identifiers

PMID31007904
PMCPMC6474678
OpenAlexW2168689019

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.