Evidence map›Paper›PMID 31007720›Full record

ArticleTherapeutic advances in gastroenterology2019

Cost savings following faecal microbiota transplantation for recurrent

Emilie Dehlholm-Lambertsen, Bianca K Hall, Simon M D Jørgensen, Christine W Jørgensen, Mia E Jensen, Sara Larsen, Josephine S Jensen, Lars Ehlers, Jens F Dahlerup, Christian L Hvas

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Treatment of RecurrentJournal of inflammation research · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Emilie Dehlholm-LambertsenSchool of Medicine and Health (SMH), Aalborg University, Denmark.
Bianca K HallSchool of Medicine and Health (SMH), Aalborg University, Denmark.
Simon M D JørgensenDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-5135-7435
Christine W JørgensenSchool of Medicine and Health (SMH), Aalborg University, Denmark.
Mia E JensenSchool of Medicine and Health (SMH), Aalborg University, Denmark.
Sara LarsenSchool of Medicine and Health (SMH), Aalborg University, Denmark.
Josephine S JensenSchool of Medicine and Health (SMH), Aalborg University, Denmark.
Lars EhlersDepartment of Business and Management, Danish Center for Healthcare Improvements, Aalborg University, Aalborg, Denmark.
Jens F DahlerupDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Christian L HvasDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200 Aarhus N, Denmark.ORCID https://orcid.org/0000-0001-7973-7184
Aalborg University · DKAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrent

methodsThis was an observational single-centre study, carried out in a public teaching hospital. We included all patients referred for rCDI from January 2014 through December 2015 and documented costs related to donor screening, laboratory processing, and clinical FMT application. We calculated patient-related hospital costs 1 year before FMT (pre-FMT) and 1 year after FMT (post-FMT). Sensitivity analyses were applied to assess the robustness of the results.

resultsWe included 50 consecutive adult patients who had a verified diagnosis of rCDI and were referred for FMT. The average cost of an outpatient FMT procedure if donor faeces were applied by colonoscopy was €3,326 per patient and €2,864 if donor faeces were applied using a nasojejunal tube. The total annual pre-FMT hospital costs per patient were €56,415 (95% confidence interval (CI) 41,133-71,697), and these costs dropped by 42% to €32,816 (22,618-42,014) post-FMT (

conclusionsIn a public hospital with an implemented FMT service, the average cost of FMT applied by either colonoscopy or nasojejunal tube was €3,095. Total hospital costs dropped by 42% the first year after FMT. The reduction was mainly caused by reductions in the number of hospital admissions and in length of stay.

Indexed as

Clostridium difficile infectionfaecal microbiota transplantationhealth economics

Identifiers

PMID31007720
PMCPMC6460887
OpenAlexW2924749311

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.