Evidence map›Paper›PMID 31007506›Full record

ArticleNigerian journal of surgery : official publication of the Nigerian Surgical Research Society

Comparison of Vacuum-Assisted Closure Therapy and Conventional Dressing on Wound Healing in Patients with Diabetic Foot Ulcer: A Randomized Controlled Trial.

Sangma M D James, Sathasivam Sureshkumar, Thirthar P Elamurugan, Naik Debasis, Chellappa Vijayakumar, Chinnakali Palanivel

3 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 32 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 7 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04093635 unknown statusnot on this map

Role of Negative Pressure Wound Therapy in the Management of Diabetic Foot Ulcers

TypeobservationalSponsorAssiut UniversityRan2019 to 2021Enrolled40ConditionsDiabetic Foot UlcerArmsNegative Pressure Wound Therapy
NCT04959071 nacompletednot on this map

Comparison of the Mean Healing Time of Wound After Vacuum Assisted Closure (VAC) Versus Conventional Dressing in Diabetic Foot Ulcer Patients

TypeinterventionalSponsorBahria UniversityRan2020 to 2020Enrolled60ConditionsDiabetic Foot Ulcer, Healing Delayed, Wound, FootArmsVacuum assisted closure VAC vs conventional dressing
NCT07758855 nacompletednot on this map

Effects of the Lunwell® Nanotechnology-Based Silver Dressing on Infected Diabetic Foot Wounds: A Prospective Controlled Study

TypeinterventionalSponsorAnkara City Hospital BilkentRan2024 to 2026Enrolled107ConditionsDiabetic Ulcers on Both FeetArmsNanotechnological silver-coated wound dressing, Sterile saline-moistened gauze dressing
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 7 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Assessment of wound healing following wall-mounted negative-pressure wound therapy using wound bed score.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sangma M D JamesDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Sathasivam SureshkumarDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Thirthar P ElamuruganDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Naik DebasisDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Chellappa VijayakumarDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Chinnakali PalanivelDepartment of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVacuum-assisted closure (VAC) therapy has been shown to be beneficial in a variety of wounds. However, evidence of its benefit in diabetic foot ulcers (DFUs), especially with respect to Indian population, is sparse. METHODOLOGY: This randomized controlled trial included DFUs of Wagner's Grades 1 and 2. Patients were further stratified with respect to DFU size <10 cm and ≥10 cm. Patients with vascular disease, osteomyelitis, and bilateral DFUs were excluded from the study. The enrolled patients were randomized to receive VAC therapy or conventional dressing. The time to wound healing, granulation tissue formation, and complications such as pain, infection, and bleeding were compared between the two groups.

resultsA total of sixty patients were randomized, of which 27 in each group were analyzed. The mean time to healing in days was significantly less in VAC group (22.52 vs. 3.85;

conclusionVAC therapy significantly decreases the time to complete wound healing, hastens granulation tissue formation, and reduces the ulcer area compared to conventional dressing. The study did not find any significant increase in the bleeding and infection in the VAC therapy group.

Indexed as

Diabetic foot ulcergranulationnegative pressure wound therapyvacuum-assisted closure therapywound healing

Identifiers

PMID31007506
PMCPMC6452767
OpenAlexW2921528165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.