Evidence map›Paper›PMID 31007402›Full record

ArticleChemical engineering & technology2018

Fermentation Titer Optimization and Impact on Energy and Water Consumption during Downstream Processing.

Vasileios Pothakos, Nadine Debeer, Ignace Debonne, Asier Rodriguez, John N Starr, Todd Anderson

Abstract read
In one paragraph

Article in Chemical engineering & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vasileios PothakosCargill R&D Centre Europe BVBA Havenstraat 84 1800 Vilvoorde Belgium.
Nadine DebeerCargill R&D Centre Europe BVBA Havenstraat 84 1800 Vilvoorde Belgium.
Ignace DebonneCargill R&D Centre Europe BVBA Havenstraat 84 1800 Vilvoorde Belgium.
Asier RodriguezCargill R&D Centre Europe BVBA Havenstraat 84 1800 Vilvoorde Belgium.
John N StarrEngineering R&D, Cargill, Inc P.O. Box 9300 MN 55440 Minneapolis USA.
Todd AndersonCargill R&D Centre Europe BVBA Havenstraat 84 1800 Vilvoorde Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A common focus of fermentation process optimization is the product titer. Different strategies to boost fermentation titer target whole-cell biocatalyst selection, process control, and medium composition. Working at higher product concentrations reduces the water that needs to be removed in the case of aqueous systems and, therefore, lowers the cost of downstream separation and purification. Different approaches to achieve higher titer in fermentation are examined. Energy and water consumption data collected from different Cargill fermentation plants, i.e., ethanol, lactic acid, and 2-keto-

Indexed as

Downstream processingEnergy savingMicrobial fermentationTiter increaseWater reduction

Identifiers

PMID31007402
PMCPMC6472596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.