Trial reportIndian journal of ophthalmology2019
Glue-assisted retinopexy for rhegmatogenous retinal detachments (GuARD): A novel surgical technique for closing retinal breaks.
Trial report in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Adhesive bioactive materials in ocular applications: Toward smart, regenerative, and minimally invasive therapies.Bioactive materials · 2026Review
- Suprachoroidal VIsco-bucKlING versus gas tamponade for the treatment of rhegmatogenous retinal detachment (VIKING): study protocol for a multi-centre, randomised, controlled feasibility study.Pilot and feasibility studies · 2026Article
- Clinical outcomes of fibrin glue assisted hemostasis in persistent intraoperative optic disc bleeding.International journal of retina and vitreous · 2026Article
- Fibrin Glue-Assisted Pretreated Lyophilized Human Amniotic Membrane Technique for Retinal Detachment With Inferior Retinal Break.Retina (Philadelphia, Pa.) · 2025Article
- A review of rhegmatogenous retinal detachment: past, present and future.Wiener medizinische Wochenschrift (1946) · 2025Review
- Cyanoacrylate glue for iatrogenic retinal breaks during vitrectomy in stage 5 familial exudative vitreoretinopathy.Frontiers in medicine · 2024Article
- Tissue Adhesives for the Management of Corneal Perforations and Challenging Corneal Conditions.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Retinal surgery quality indicators for uncomplicated primary rhegmatogenous retinal detachment without a national registry.Acta ophthalmologica · 2022Article
- Biocompatibility and Efficacy of a Linearly Cross-Linked Sodium Hyaluronic Acid Hydrogel as a Retinal Patch in Rhegmatogenous Retinal Detachment Repairment.Frontiers in bioengineering and biotechnology · 2022Article
- Advances in biomaterials as a retinal patch for the repair of rhegmatogenous retinal detachment.Frontiers in bioengineering and biotechnology · 2022Review
- New epiretinal implant with integrated sensor chips for optical capturing shows a good biocompatibility profile in vitro and in vivo.Biomedical engineering online · 2021Article
- Reattachment of Rhegmatogenous Retinal Detachment via Fibrin Tissue Adhesive.Korean journal of ophthalmology : KJO · 2021Article
- Versatility of use of fibrin glue in wound closure and vitreo-retinal surgery.International journal of retina and vitreous · 2021Article
- Application of Collagen I and IV in Bioengineering Transparent Ocular Tissues.Frontiers in surgery · 2021Review
- Lyophilized amniotic membrane patch (LAMPatch) as a replacement of tamponades in the treatment of primary rhegmatogenous retinal detachment.International journal of retina and vitreous · 2020Article
- Retinal Tamponades: Current Uses and Future Technologies.Current ophthalmology reports · 2020Article
- Commentary: Fibrin sealant for temporary retinopexy.Indian journal of ophthalmology · 2019Article
- Commentary: Fibrin glue in rhegmatogenous retinal detachment repair-Are we there yet?Indian journal of ophthalmology · 2019Article
- Commentary: Sealing breaks comfortably- A novel approach to retinopexy without positioning.Indian journal of ophthalmology · 2019Article
- Autologous Platelet-Rich Fibrin in the Treatment of Refractory Macular Holes.Case reports in ophthalmological medicine · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study describes a novel surgical technique of fibrin glue-assisted retinopexy for rhegmatogenous retinal detachment (GuARD) without oil or gas tamponade after pars plana vitrectomy (PPV). Methods: This pilot clinical trial included five eyes of five patients with rhegmatogenous retinal detachments (RD). A complete PPV was done in all cases followed by fluid-air exchange, laser photocoagulation around the break/s, and application of 0.1-0.2 mL of fibrin glue. No air, long-acting gas or silicone oil was used subsequently. No specific postoperative positioning was prescribed. The primary outcome measure was efficacy of the procedure defined as successful anatomical retinal reattachment. Secondary outcome measures were postoperative improvement in best corrected visual acuity (BCVA) and complications. Results: The median age of patients was 55 (range: 36-61 years) years and median duration of symptoms was 15 (range: 7-60) days. All eyes were pseudophakic, four eyes had inferior and one eye had total RD. Successful retinal reattachment was achieved in all (100%) cases and was maintained at the end of 3-8 months of follow-up. The median BCVA improved from 20/100 preoperatively to 20/80 at 1-week and 20/50 at 1-month postoperatively. None of the eyes had any postoperative complications such as elevated intraocular pressures or unexpected inflammation. Conclusion: The findings of this study suggest that GuARD is a promising technique for treatment of rhegmatogenous RD that may allow early visual recovery while avoiding the problems of gas or oil tamponade and obviating the need of postoperative positioning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.