Evidence map›Paper›PMID 31007132›Full record

ArticleTissue engineering. Part C, Methods2019

Fully Three-Dimensional Bioprinted Skin Equivalent Constructs with Validated Morphology and Barrier Function.

Kristy Derr, Jinyun Zou, Keren Luo, Min Jae Song, G Sitta Sittampalam, Chao Zhou, Sam Michael, Marc Ferrer, Paige Derr

Abstract read
In one paragraph

Article in Tissue engineering. Part C, Methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Skin substitutes: from conventional to 3D bioprinting.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro.Toxicology in vitro : an international journal published in association with BIBRA · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kristy Derr1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
Jinyun Zou2 Department of Electrical and Computer Engineering, Bethlehem, Pennsylvania.
Keren Luo2 Department of Electrical and Computer Engineering, Bethlehem, Pennsylvania.
Min Jae Song3 National Eye Institute, National Institutes of Health, Rockville, Maryland.
G Sitta Sittampalam1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
Chao Zhou2 Department of Electrical and Computer Engineering, Bethlehem, Pennsylvania.
Sam Michael1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
Marc Ferrer1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
Paige Derr1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.

Funding

High throughput optical coherence tomography (OCT)-based imaging platform for label-free, non-invasive characterization of 3D tumor spheroids.R01EB025209 · NIBIB · WASHINGTON UNIVERSITY · PI ZHOU, CHAO · 2017 to 2021
$1.4M
NIBIB NIH HHS R01 EB025209
6 · The paper itself

Abstract

impact statementThis article describes a method for the biofabrication of skin tissue equivalents in a multiwell plate format. The technique and results overcome shortcomings of previously published engineering methods, and show good architecture and barrier function from well to well; thus it may be used for compound functional testing and for the development of disease tissue models for screening.

Indexed as

BioprintingPrinting, Three-DimensionalSkin, ArtificialCell SurvivalElectric ConductivityEpidermisHumansHydrogelsImaging, Three-DimensionalLamininMembrane GlycoproteinsReproducibility of ResultsTissue ScaffoldsTissue SurvivalHydrogelsLamininMembrane Glycoproteinsnidogenbarrier functionbioprintinghigh-throughput screeningkeratinocytesskin

Identifiers

PMID31007132
PMCPMC6589501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.