ArticleACS chemical neuroscience2019
Recalibrating the Existence of New Neurons in Adult Brain.
Article in ACS chemical neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Neuroinflammation-A Crucial Factor in the Pathophysiology of Depression-A Comprehensive Review.Biomolecules · 2025Review
- Multimodal treatment for spinal cord injury: a sword of neuroregeneration upon neuromodulation.Neural regeneration research · 2020Review
- Anatomical variations of the dentate gyrus in normal adult brain.Surgical and radiologic anatomy : SRA · 2020Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
New neurons were shown to born throughout adulthood, a process known as neurogenesis. Last year, the human hippocampal neurogenesis field was flipped on its head by a paper in Nature from Sorrells et al. questioning the presence of human hippocampal neurogenesis during adulthood ( Sorrells, S.F. et al. 2018 Nature , 555 , 377 - 381 ). Now, a new study by Moreno-Jiménez et al. reported that human brain can make new neurons well beyond middle age until the tenth decade of their life, and earlier studies have failed to find the neurogenesis due to its flawed methods. This paper also finds that production of new neurons drastically drops in patients suffering from Alzheimer's disease. Here, we discuss key findings of this paper, emphasizing how improved protocols and tissue preservation lead to visualization of adult neurogenesis and further highlighting in what way this drop of neurogenesis in Alzheimer's disease brain could possibly open new roads to therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.