Evidence map›Paper›PMID 31006849›Full record

ArticleCancer2019

The role of cancer in marijuana and prescription opioid use in the United States: A population-based analysis from 2005 to 2014.

Kathryn R Tringale, Minh-Phuong Huynh-Le, Mia Salans, Deborah C Marshall, Yuyan Shi, Jona A Hattangadi-Gluth

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Cannabis use among cancer survivors: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2026
    Pooled it
  2. Pooled it
  3. Cannabis use and perceptions among rural and urban cancer patients and survivors from a Pennsylvania cancer center.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Post-diagnosis cannabis use and its association with health status and quality of life in cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Cannabis stigma and symptom management considerations in cancer survivors: a mixed-methods exploration of patient perspectives.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  6. Article
  7. Characteristics of Cannabis Use Among Head and Neck Cancer Survivors.Laryngoscope investigative otolaryngology · 2025
    Article
  8. Prevalence and determinants of cigarette-cannabis co-use among US cancer survivors.Journal of cancer survivorship : research and practice · 2025
    Article
  9. Article
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  11. Patient out-of-pocket costs for cannabis use during cancer treatment.Journal of the National Cancer Institute. Monographs · 2024
    Article
  12. Article
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  20. Current cannabis use and pain management among US cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kathryn R TringaleSchool of Medicine, University of California San Diego, La Jolla, California.ORCID 0000-0002-1506-4870
Minh-Phuong Huynh-LeDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, California.ORCID 0000-0002-5025-4709
Mia SalansSchool of Medicine, University of California San Diego, La Jolla, California.
Deborah C MarshallDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, California.
Yuyan ShiDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, California.
Jona A Hattangadi-GluthDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, California.
University of California San Diego · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
San Diego Clinical and Translational Research InstituteUL1TR000100 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2012 to 2015
$19.7M
UC San Diego Clinical and Translational Research InstituteTL1TR001443 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2019
$3.4M
Neighborhood Physical, Economic, and Socioeconomic Environment In Relation to Marijuana Use and DisorderR01DA042290 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHI, YUYAN · 2017 to 2020
$2.6M
San Diego Clinical and Translational Research InstituteKL2TR000099 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2012 to 2014
$1.1M
NCATS NIH HHS KL2 TR000099NCATS NIH HHS TL1 TR001443NCATS NIH HHS UL1 TR000100NCATS NIH HHS UL1 TR001442NIDA NIH HHS R01 DA042290
6 · The paper itself

Abstract

backgroundFor patients with cancer, marijuana may be an alternative to prescription opioid analgesics. This study analyzed self-reported marijuana and prescription opioid use among people with cancer over a 10-year time period.

methodsPopulation-based data sets from the US National Health and Nutrition Examination Survey between 2005 and 2014 were compiled for respondents aged 20 to 60 years. Respondents with cancer and respondents without cancer were propensity score-matched (1:2) by demographics to compare substance use. Outcomes included current marijuana and prescription opioid use (ie, within the past 30 days). Pearson chi-square tests and logistic regressions were performed; a 2-tailed P value < .05 was significant.

resultsThere were 19,604 respondents, and 826 people with cancer were matched to 1652 controls. Among the respondents with cancer, 40.3% used marijuana within the past year, and 8.7% used it currently. Respondents with cancer were significantly more likely to use prescription opioids (odds ratio [OR], 2.43; 95% CI, 1.68-3.57; P < .001). Cancer was not associated with current marijuana use in a multivariable conditional logistic regression but was associated with current opioid use (OR, 1.82; 95% CI, 1.17-2.82; P = .008). Among all survey respondents, the odds of marijuana use significantly increased over time (OR, 1.05; 95% CI, 1.01-1.10; P = .012), whereas the odds of opioid use did not significantly change. There were no significant differences in the longitudinal odds of marijuana or opioid use over time between respondents with a cancer diagnosis and those without one.

conclusionsThis population-based analysis revealed a considerable proportion of respondents with cancer self-reporting marijuana use (40.3%) and a significantly higher prevalence of opioid use among respondents with cancer. In the midst of an opioid epidemic, an evolving political landscape, and new developments in oncology, quantifying the prevalence of opioid and marijuana use in the US population, especially among patients with cancer, is particularly relevant. Although opioid use did not significantly change from 2005 to 2014 among all respondents, marijuana use did increase, likely reflecting increased availability and legislative changes. A cancer diagnosis did not significantly affect longitudinal opioid or marijuana use.

Indexed as

AdultAnalgesics, OpioidCannabisCase-Control StudiesFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedNeoplasmsNutrition SurveysPrescription Drug OverusePrevalencePrognosisTime FactorsAnalgesics, Opioidanalgesicscancerhealth policymarijuana useopioidprevalenceself-report

Identifiers

PMID31006849
PMCPMC6810711
OpenAlexW2941246905

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.