Evidence map›Paper›PMID 31006766›Full record

ArticleZoological research2019

Passive eye movements induced by electromagnetic force (EMF) in rats.

Yue Yu, Jun Huang, Chun-Ming Zhang, Tian-Wen Chen, David S Sandlin, Shao-Xun Wang, Alberto A Arteaga, Jerome Allison, Yang Ou, Susan Warren and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zoological research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Yue YuDepartments of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
Jun HuangDepartments of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
Chun-Ming ZhangDepartment of Otolaryngology, First Affiliated Hospital, Shanxi Medical University, Taiyuan Shanxi 030001, China.
Tian-Wen ChenDepartments of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
David S SandlinMD/PhD Program, University of Mississippi Medical Center, Jackson MS 39216, USA.
Shao-Xun WangDepartments of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
Alberto A ArteagaDepartments of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
Jerome AllisonNeurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
Yang OuDepartments of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
Susan WarrenNeurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
Paul MayNeurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA.
Hong ZhuDepartments of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA; E-mail:wzhou@umc.edu.
Wu ZhouDepartments of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson MS 39216, USA;E-mail:hozhu@umc.edu.
University of Mississippi Medical Center · USFirst Hospital of Shanxi Medical University · CNJackson Memorial Hospital · US

Funding

Neural mechanisms of sound activation of vestibular systemR01DC012060 · NIDCD · UNIVERSITY OF MISSISSIPPI MED CTR · PI ZHU, HONG · 2012 to 2016
$1.9M
Neural mechanisms of active gaze stabilization (AGS) in monkeysR01DC014930 · NIDCD · UNIVERSITY OF MISSISSIPPI MED CTR · PI MAY, PAUL J, ZHOU, WU · 2015 to 2019
$1.6M
Horizontal rectus muscle forces during combined eye head gaze shiftsR21EY025550 · NEI · UNIVERSITY OF MISSISSIPPI MED CTR · PI ZHOU, WU · 2015 to 2016
$419k
NEI NIH HHS R21 EY025550NIDCD NIH HHS R01 DC012060NIDCD NIH HHS R01 DC014930
6 · The paper itself

Abstract

Accurate information on eye position in the orbit is available from visual feedback, efference copy of the oculomotor commands and proprioceptive signals from the extraocular muscles (EOM). Whereas visual feedback and oculomotor commands have been extensively studied, central processing of EOM proprioceptive signals remains to be elucidated. A challenge to the field is to develop an approach to induce passive eye movements without physically contacting the eyes. A novel method was developed to generate passive eye movements in rats. A small rare-earth magnet disk (0.7 mm diameter, 0.5 mm thickness) was attached to the surface of a rat's eyeball. A metal rod (5 mm diameter) wrapped with an electromagnetic (EM) coil was placed near the magnet (8-15 mm). By passing currents to the EM coil, electromagnetic force (EMF) was generated and acted upon the magnet and induced passive eye movements. The EMF induced well-defined passive eye movements, whose directions were dependent on current polarity and amplitudes and peak velocities were dependent on current intensity and duration. Peak velocities of the EMF-induced eye movements were linearly related to amplitudes, exhibiting main sequence relationships similar to that of saccades in awake rats and eye movements induced by electrical microstimulation of the abducens nucleus in anesthetized rats. Histological examination showed that repetitive EMF stimulations did not appear to result in damages in the EOM fibers. These results validated the EMF approach as a novel tool to investigate EOM proprioceptive signals and their roles in visual localization and gaze control.

Indexed as

Electrophysiological PhenomenaAnimalsElectromagnetic FieldsEye MovementsFemaleProprioceptionRatsRats, Long-EvansExtraocular musclesEye movementProprioceptionStretch reflex

Identifiers

PMID31006766
PMCPMC6591162
OpenAlexW2950106710

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.