Evidence map›Paper›PMID 31006406›Full record

SynthesisEpidemiology and psychiatric sciences2019

Seasonality and symptoms of depression: A systematic review of the literature.

Simon Øverland, Wojtek Woicik, Lindsey Sikora, Kristoffer Whittaker, Hans Heli, Fritjof Stein Skjelkvåle, Børge Sivertsen, Ian Colman

Abstract readSystematic Review
In one paragraph

Synthesis in Epidemiology and psychiatric sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Simon ØverlandDivision of Mental and Physical Health, Norwegian Institute of Public Health, Bergen, Norway.ORCID https://orcid.org/0000-0001-6967-9355
Wojtek WoicikDepartment of Psychological Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.
Lindsey SikoraHealth Sciences Library, University of Ottawa, Ottawa, Ontario, Canada.
Kristoffer WhittakerThe Research Institute, Modum Bad Psychiatric Center, Vikersund, Norway.
Hans HeliLovisenberg Diaconal Hospital, Oslo, Norway.
Fritjof Stein SkjelkvåleInnlandet hospital trust, Norway.
Børge SivertsenDivision of Mental and Physical Health, Norwegian Institute of Public Health, Bergen, Norway.
Ian ColmanSchool of Epidemiology & Public Health, University of Ottawa, Ottawa, Canada.ORCID https://orcid.org/0000-0001-5924-0277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsLay opinions and published papers alike suggest mood varies with the seasons, commonly framed as higher rates of depression mood in winter. Memory and confirmation bias may have influenced previous studies. We therefore systematically searched for and reviewed studies on the topic, but excluded study designs where explicit referrals to seasonality were included in questions, interviews or data collection.

methodsSystematic literature search in Cochrane database, DARE, Medline, Embase, PsychINFO and CINAHL, reporting according to the PRISMA framework, and study quality assessment using the Newcastle-Ottawa scale. Two authors independently assessed each study for inclusion and quality assessment. Due to large heterogeneity, we used a descriptive review of the studies.

resultsAmong the 41 included studies, there was great heterogeneity in regards to included symptoms and disorder definitions, operationalisation and measurement. We also observed important heterogeneity in how definitions of 'seasons' as well as study design, reporting and quality. This heterogeneity precluded meta-analysis and publication bias analysis. Thirteen of the studies suggested more depression in winter. The remaining studies suggested no seasonal pattern, seasonality outside winter, or inconclusive results.

conclusionsThe results of this review suggest that the research field of seasonal variations in mood disorders is fragmented, and important questions remain unanswered. There is some support for seasonal variation in clinical depression, but our results contest a general population shift towards lower mood and more sub-threshold symptoms at regular intervals throughout the year. We suggest future research on this issue should be aware of potential bias by design and take into account other biological and behavioural seasonal changes that may nullify or exacerbate any impact on mood.

Indexed as

HumansSeasonal Affective DisorderSeasonsAdmissionsantidepressantsdepressiondepressive symptomsmood disorderspostpartum depressionseasonalitysystematic review

Identifiers

PMID31006406
PMCPMC8061295

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.