Evidence map›Paper›PMID 31006329›Full record

ArticleHypertension (Dallas, Tex. : 1979)2019

2017 Pediatric Hypertension Guidelines Improve Prediction of Adult Cardiovascular Outcomes.

Tingting Du, Camilo Fernandez, Rupert Barshop, Wei Chen, Elaine M Urbina, Lydia A Bazzano

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Review
  5. Review
  6. Pre- and postnatal exposure to PMEnvironmental research · 2026
    Article
  7. Article
  8. Obesity, Hypertension and Brain Health.Current hypertension reports · 2025
    Review
  9. Article
  10. Article
  11. Rising pressure to understand the risks of hypertension in children with narcolepsy type 1.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Tingting DuFrom the Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan China (D.T.).
Camilo FernandezDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA (D.T., F.C., B.R., C.W., B.L.).
Rupert BarshopDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA (D.T., F.C., B.R., C.W., B.L.).
Wei ChenDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA (D.T., F.C., B.R., C.W., B.L.).
Elaine M UrbinaHeart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (U.E.M.).
Lydia A BazzanoDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA (D.T., F.C., B.R., C.W., B.L.).
Tulane University · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI JUDD E SHELLITO · 2012 to 2026
$69.1M
Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Katherine Teresa Mills · 2016 to 2026
$25.3M
EVOLUTION OF CARDIOVASCULAR RISK WITH NORMAL AGINGR01AG016592 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2000 to 2015
$11.7M
Tulane Building Interdisciplinary Research Careers in Women's Health (BIRCWH)K12HD043451 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI KROUSEL-WOOD, MARIE · 2002 to 2023
$9.9M
Lifespan Cardiovascular Risk Exposures and Alzheimer-related brain health: Bogalusa Heart StudyRF1AG041200 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI BAZZANO, LYDIA, CARMICHAEL, OWEN T. · 2019 to 2022
$4.2M
The Role of Vascular Aging in Cognitive and Physical Function - Diversity SupplementR01AG041200 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI BAZZANO, LYDIA · 2012 to 2017
$2.9M
Long-Term Burden of Maternal Cardiovascular Risk Factors and Birth OutcomesR01HD069587 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI HARVILLE, EMILY WHEELER · 2012 to 2015
$2.1M
Childhood Secondhand Smoke and Longitudinal Cardiovascular Risk ProfileR01ES021724 · NIEHS · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2012 to 2014
$1.8M
Building Interdisciplinary Research Careers in Women's HealthK12AR084224 · NIAMS · TULANE UNIVERSITY OF LOUISIANA · PI Marie Krousel-Wood · 2024 to 2026
$1.6M
Digital biomarkers of Alzheimers-related brain health and functionR21AG057983 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI BAZZANO, LYDIA, URBINA, ELAINE MOTT · 2018 to 2020
$812k
NIAMS NIH HHS K12 AR084224NIA NIH HHS R01 AG016592NIA NIH HHS R01 AG041200NIA NIH HHS R21 AG057983NIA NIH HHS RF1 AG041200NICHD NIH HHS K12 HD043451NICHD NIH HHS R01 HD069587NIEHS NIH HHS R01 ES021724NIGMS NIH HHS P20 GM109036NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

We aimed to evaluate the consequences of the 2017 pediatric hypertension definitions, compared with the 2004 pediatric hypertension definitions on the prevalence of hypertension and to assess the performance of these 2 sets of guidelines in predicting adult hypertension, metabolic syndrome, and left ventricular hypertrophy (LVH). This longitudinal study consisted of 3940 children (47% male; ages 3-18 years) who came from the Bogalusa Heart Study with 36-year follow-up since childhood. Hypertension was identified in 7% and 11% as defined in the 2004 and 2017 guidelines, respectively. The 2004 and 2017 guidelines demonstrated similar associations with adulthood hypertension, metabolic syndrome, and LVH. However, the proportion of children identified as having hypertension who developed adult LVH increased from 12% when defined by the 2004 guidelines to 19% when defined by the 2017 guidelines. Overall, the 329 (8%) children who were reclassified to higher blood pressure categories by the 2017 guidelines were more likely than their propensity score-matched normotensive counterparts to develop hypertension, metabolic syndrome, and LVH in later life, whereas 38 (1%) children who were reclassified to lower blood pressure categories by the 2017 guidelines had similar cardiometabolic outcomes to their propensity score-matched normotensive counterparts. Hence, children who were reclassified to higher blood pressure categories based on 2017 guidelines were at increased risk of developing hypertension, metabolic syndrome, and LVH in later life. The 2017 guidelines identified a group of children with adverse metabolic profile and cardiometabolic outcomes, whose cardiovascular risk seemed to be underestimated using the 2004 guidelines.

Indexed as

Guidelines as TopicAdolescentAdultBlood PressureChildChild, PreschoolCross-Sectional StudiesEchocardiographyFemaleFollow-Up StudiesHeart VentriclesHumansHypertensionHypertrophy, Left VentricularIncidenceMaleblood pressurecardiovascular diseasehypertensionmetabolic syndromepropensity score

Identifiers

PMID31006329
PMCPMC6673663
OpenAlexW2939959725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.