Evidence map›Paper›PMID 31006227›Full record

ArticleUltrasonography (Seoul, Korea)2019

Contrast-enhanced ultrasound of hepatocellular carcinoma: where do we stand?

Tommaso Vincenzo Bartolotta, Adele Taibbi, Massimo Midiri, Roberto Lagalla

Abstract read
In one paragraph

Article in Ultrasonography (Seoul, Korea), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Microvascular Imaging of Hepatic Hemangiomas.Diagnostics (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. The Role of Molecular Imaging in Personalized Medicine.Journal of personalized medicine · 2023
    Review
  17. Review
  18. Local-Regional Treatment of Hepatocellular Carcinoma: A Primer for Radiologists.Radiographics : a review publication of the Radiological Society of North America, Inc · 2022
    Article
  19. Contrast-enhanced ultrasound for assessing blood flow modulation of hepatocellular carcinoma by hydralazine.IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tommaso Vincenzo BartolottaDepartment of Radiology, University of Palermo, Palermo, Italy.
Adele TaibbiDepartment of Radiology, University of Palermo, Palermo, Italy.
Massimo MidiriDepartment of Radiology, University of Palermo, Palermo, Italy.
Roberto LagallaDepartment of Radiology, University of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast-enhanced ultrasound (CEUS) represents a significant breakthrough in ultrasonography (US), and it is being increasingly used for the evaluation of focal liver lesions (FLLs). CEUS is unique in that it allows non-invasively assessment of liver perfusion in real time throughout the vascular phase, which has led to dramatic improvements in the diagnostic accuracy of US in the detection and characterization of FLLs, the choice of therapeutic procedures, and the evaluation of response. Currently, CEUS is included as a part of the suggested diagnostic work-up of FLLs, including in cirrhotic patients with hepatocellular carcinoma, resulting in better patient management and cost-effective delivery of therapy.

Indexed as

Contrast-enhanced ultrasonographyHepatocellular carcinomaLiverLiver cirrhosisUltrasonographyUltrasound contrast media

Identifiers

PMID31006227
PMCPMC6595127

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.