Evidence map›Paper›PMID 31006090›Full record

ArticleCellular and molecular neurobiology2019

Age-Dependency of Levetiracetam Effects on Exocytotic GABA Release from Nerve Terminals in the Hippocampus and Cortex in Norm and After Perinatal Hypoxia.

Natalia Pozdnyakova, Marina Dudarenko, Tatiana Borisova

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Natalia PozdnyakovaThe Department of Neurochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, 9 Leontovicha Str, Kiev, 01030, Ukraine.
Marina DudarenkoThe Department of Neurochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, 9 Leontovicha Str, Kiev, 01030, Ukraine.
Tatiana BorisovaThe Department of Neurochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, 9 Leontovicha Str, Kiev, 01030, Ukraine. tborisov@biochem.kiev.ua.ORCID http://orcid.org/0000-0002-6533-1420
National Academy of Sciences of Ukraine · UA

Funding

Ministry of Education and Science of Ukraine 2019-2020National Academy of Sciences of Ukraine #19-2019National Academy of Sciences of Ukraine #35-2019National Academy of Sciences of Ukraine #9/1-2019State Fund For Fundamental Research # F76/13-2018
6 · The paper itself

Abstract

Perinatal hypoxia can lead to multiple chronic neurological deficits, e.g., mental retardation, behavioral abnormalities, and epilepsy. Levetiracetam (LEV), 2S-(2-oxo-1-pyrrolidiny1) butanamide, is an anticonvulsant drug with proven efficiency in treating patients with focal and generalized seizures. Rats were underwent hypoxia and seizures at the age of 10-12 postnatal days (pd). The ambient level and depolarization-induced exocytotic release of [

Indexed as

AgingAnimalsAnimals, NewbornExocytosisgamma-Aminobutyric AcidHippocampusHypoxiaLevetiracetamMaleNerve EndingsRats, Wistargamma-Aminobutyric AcidLevetiracetamBrain developmentCortexExocytosisGABAHippocampusLevetiracetamNerve terminalsPerinatal hypoxia

Identifiers

PMID31006090
PMCPMC11462832
OpenAlexW2938765723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.