Evidence map›Paper›PMID 31006059›Full record

ArticleArchives of toxicology2019

The role of fuel type and combustion phase on the toxicity of biomass smoke following inhalation exposure in mice.

Yong Ho Kim, Charly King, Todd Krantz, Marie M Hargrove, Ingrid J George, John McGee, Lisa Copeland, Michael D Hays, Matthew S Landis, Mark Higuchi and 2 more

Open access · greenAbstract read
In one paragraph

Article in Archives of toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
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  5. DifferentialACS ES&T air · 2025
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  13. Repeated exposure to eucalyptus wood smoke alters pulmonary gene and metabolic profiles in male Long-Evans rats.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yong Ho KimEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
Charly KingEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
Todd KrantzEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
Marie M HargroveOak Ridge Institute for Science and Education, Research Triangle Park, NC, 27711, USA.
Ingrid J GeorgeAir and Energy Management Division, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
John McGeeEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
Lisa CopelandEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
Michael D HaysAir and Energy Management Division, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
Matthew S LandisExposure Methods and Measurement Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
Mark HiguchiEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
Stephen H GavettEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.
M Ian GilmourEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA. gilmour.ian@epa.gov.ORCID http://orcid.org/0000-0002-3070-6704
Environmental Protection Agency · USTriangle · US

Funding

Intramural EPA EPA999999Joint Fire Science Program 14-1-04-16
6 · The paper itself

Abstract

The characteristics of wildland fire smoke exposures which initiate or exacerbate cardiopulmonary conditions are unclear. We previously reported that, on a mass basis, lung toxicity associated with particulate matter (PM) from flaming smoke aspirated into mouse lungs is greater than smoldering PM. In this study, we developed a computer-controlled inhalation system which can precisely control complex biomass smoke emissions from different combustion conditions. This system was used to examine the toxicity of inhaled biomass smoke from peat, eucalyptus, and oak fuels generated under smoldering and flaming phases with emissions set to the same approximate concentration of carbon monoxide (CO) for each exposure (60-110 ppm), resulting in PM levels of ~ 4 mg/m

Indexed as

BiomassAir PollutantsAnimalsCarbon MonoxideEucalyptusFemaleInhalation ExposureLung DiseasesMiceMice, Inbred BALB CNeutrophil InfiltrationParticulate MatterQuercusRespiratory Function TestsSmokeSoilAir PollutantsCarbon MonoxideParticulate MatterSmokeSoilBiomass smokeInhalationLung toxicityParticulate matterWildland fire smoke

Identifiers

PMID31006059
PMCPMC6991149
OpenAlexW2939685495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.