Evidence map›Paper›PMID 31005914›Full record

ArticleBMJ open2019

Pathways and associated costs of care in patients with confirmed and presumptive tuberculosis in Tanzania: A cross-sectional study.

Grace Mhalu, Jerry Hella, Francis Mhimbira, Khadija Said, Thomas Mosabi, Yeromin P Mlacha, Christian Schindler, Sébastien Gagneux, Klaus Reither, Kees de Hoogh and 3 more

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Grace MhaluIfakara Health Institute, Dar es Salaam, Tanzania.ORCID 0000-0002-0417-3027
Jerry HellaIfakara Health Institute, Dar es Salaam, Tanzania.
Francis MhimbiraIfakara Health Institute, Dar es Salaam, Tanzania.
Khadija SaidIfakara Health Institute, Dar es Salaam, Tanzania.
Thomas MosabiIfakara Health Institute, Dar es Salaam, Tanzania.
Yeromin P MlachaIfakara Health Institute, Dar es Salaam, Tanzania.
Christian SchindlerSwiss Tropical and Public Health Institute, Basel, Switzerland.
Sébastien GagneuxSwiss Tropical and Public Health Institute, Basel, Switzerland.
Klaus ReitherSwiss Tropical and Public Health Institute, Basel, Switzerland.
Kees de HooghSwiss Tropical and Public Health Institute, Basel, Switzerland.
Mitchell G WeissSwiss Tropical and Public Health Institute, Basel, Switzerland.
Elisabeth ZempSwiss Tropical and Public Health Institute, Basel, Switzerland.
Lukas FennerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess pathways and associated costs of seeking care from the onset of symptoms to diagnosis in patients with confirmed and presumptive tuberculosis (TB).

designCross-sectional study.

settingDistrict hospital in Dar es Salaam, Tanzania.

participantsBacteriologically confirmed TB and presumptive TB patients. PRIMARY AND SECONDARY OUTCOME MEASURES: We calculated distance in metres and visualised pathways to healthcare up to five visits for the current episode of sickness. Costs were described by medians and IQRs, with comparisons by gender and poverty status.

resultsOf 100 confirmed and 100 presumptive TB patients, 44% of confirmed patients sought care first at pharmacies after the onset of symptoms, and 42% of presumptive patients did so at hospitals. The median visits made by confirmed patients was 2 (range 1-5) and 2 (range 1-3) by presumptive patients. Patients spent a median of 31% of their monthly household income on health expenditures for all visits. The median total direct costs were higher in confirmed compared with presumptive patients (USD 27.4 [IQR 18.7-48.4] vs USD 19.8 [IQR 13.8-34.0], p=0.02), as were the indirect costs (USD 66.9 [IQR 35.5-150.0] vs USD 46.8 [IQR 20.1-115.3], p<0.001). The indirect costs were higher in men compared with women (USD 64.6 [IQR 31.8-159.1] vs USD 55.6 [IQR 25.1-141.1], p<0.001). The median total distance from patients' household to healthcare facilities for patients with confirmed and presumptive TB was 2338 m (IQR 1373-4122) and 2009 m (IQR 986-2976) respectively.

conclusionsPatients with confirmed TB have complex pathways and higher costs of care compared with patients with presumptive TB, but the costs of the latter are also substantial. Improving access to healthcare and ensuring integration of different healthcare providers including private, public health practitioners and patients themselves could help in reducing the complex pathways during healthcare seeking and optimal healthcare utilisation.

Indexed as

AdultAntibiotics, AntitubercularCross-Sectional StudiesFemaleHealth Care CostsHealth Planning GuidelinesHumansMalePatient Acceptance of Health CareTanzaniaTuberculosisYoung AdultAntibiotics, Antituberculardirect costshealth carehealth-seekingindirect costspathways to caretuberculosis

Identifiers

PMID31005914
PMCPMC6528007

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.