ArticleThe journal of pain2019
Adverse Childhood Experiences in Mothers With Chronic Pain and Intergenerational Impact on Children.
Article in The journal of pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Impact of parental adverse childhood experiences on children's healthcare utilisation: a systematic review.Journal of epidemiology and community health · 2026Pooled it
- Adverse childhood experience is associated with an increased risk of reporting chronic pain in adulthood: a stystematic review and meta-analysis.European journal of psychotraumatology · 2023Pooled it
- Adverse childhood experiences and adult stress eating: A secondary analysis of the Southern Community Cohort Study.Research square · 2026Article
- Pain disparities among Medicaid beneficiaries with chronic low back pain: The differential role of psychological distress.The journal of pain · 2025Article
- Adverse childhood experiences and adult stress eating.Research square · 2025Article
- Relationship between adverse childhood experiences and musculoskeletal pain: the mediating effect of depressive symptoms.BMC psychology · 2025Article
- Associations of adverse childhood experiences (ACE) with pregnancy outcomes in people with cardiac disease.European journal of obstetrics, gynecology, and reproductive biology · 2025Article
- Short-term maternal oxytocin administration may protect against poor outcomes of adverse childhood experiences in the offspring.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Intergenerational continuity of adverse childhood experiences among Mexican-origin families: Examination of intra and extra-familial adversities.Family process · 2025Article
- Examining the epigenetic transmission of risk for chronic pain associated with paternal post-traumatic stress disorder: a focus on veteran populations.Translational psychiatry · 2025Review
- Social Determinants and Consequences of Pain: Toward Multilevel, Intersectional, and Life Course Perspectives.The journal of pain · 2024Review
- Association of parental adverse childhood experiences with offspring sleep problems: the role of psychological distress and harsh discipline.Child and adolescent psychiatry and mental health · 2024Article
- Maternal and Paternal Adverse Childhood Experiences (ACEs) and Offspring Health and Wellbeing: A Scoping Review.Maternal and child health journal · 2024Article
- Patterns of maternal adverse childhood experiences and the intergenerational association of preschool children's emotional and behavioral problems.Frontiers in psychiatry · 2024Article
- Adverse childhood experiences of Korean mothers with young children: a latent class analysis.European journal of psychotraumatology · 2024Article
- Stress-Induced Changes in the Endogenous Opioid System Cause Dysfunction of Pain and Emotion Regulation.International journal of molecular sciences · 2023Review
- Associations between Adverse Childhood Experiences (ACEs) and Prenatal Mental Health and Substance Use.International journal of environmental research and public health · 2023Article
- Determinants of sleep disturbance and sleep quality in children of mothers with fibromyalgia.Archives of rheumatology · 2023Article
- The Moderating Effect of Contact with Children on the Relationship between Adverse Childhood Experiences and Depression in Adulthood among a Chinese Adult Population.International journal of environmental research and public health · 2022Article
- Prevalence of Adverse Childhood Experiences in Students with Emotional and Behavioral Disorders in Special Education Schools from a Multi-Informant Perspective.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Adverse childhood experiences (ACEs; eg, parental divorce, physical or sexual abuse) are more prevalent in individuals with chronic pain compared with the general population. Both increased maternal ACEs and chronic pain have been associated with poor physical and emotional functioning in offspring. However, the mechanisms driving these associations are poorly understood. Thus, this cross-sectional study evaluated the relation between maternal ACEs, mothers' current functioning, and children's physical and emotional functioning in a sample of mothers with chronic pain and their 8- to 12-year-old children. Results indicated a higher prevalence of ≥1 ACE in this sample of mothers with chronic pain (84%) compared with normative data from a community sample of women. Higher maternal ACE scores corresponded with lower physical and social functioning, greater anxiety and depressive symptoms, greater fatigue and sleep disturbances, and greater pain intensity and pain interference in mothers. Higher maternal ACE scores significantly correlated with higher child self-reported depressive symptoms, but not somatic symptoms or functional impairment. A path model indicated that maternal depressive symptoms accounted for the relation between higher maternal ACE scores and children's depressive symptoms. Intervening on maternal depression among mothers with chronic pain may reduce the impact of intergenerational ACE transmission. Perspective: This article presents evidence regarding the intergenerational impact of ACEs in a large sample of mothers with chronic pain and their school-aged children. Maternal depressive symptoms accounted for the relation between maternal ACEs and children's depressive symptoms providing evidence regarding targets for preventive interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.