Evidence map›Paper›PMID 31005553›Full record

ArticleAnnals of epidemiology2019

Untangling the ethical intersection of epidemiology, human subjects research, and public health.

Jennifer Salerno, Edward S Peters, Susan M Pinney, Stephanie Morain, WayWay M Hlaing

Abstract read
In one paragraph

Article in Annals of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Ethics and Collateral Findings in Pragmatic Clinical Trials.The American journal of bioethics : AJOB · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer SalernoAging, Community and Health Research Unit, School of Nursing, McMaster University, Hamilton, Ontario, Canada. Electronic address: salernoj@mcmaster.ca.
Edward S PetersEpidemiology Program, School of Public Health, Louisiana State University, New Orleans.
Susan M PinneyDepartment of Environmental Health, College of Medicine, University of Cincinnati, Cincinnati, OH.
Stephanie MorainCenter for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX.
WayWay M HlaingDivision of Epidemiology and Population Sciences, Department of Public Health Sciences, University of Miami, Miami, FL.

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI YADAV, JAGJIT S · 1992 to 2022
$35.4M
Fernald Community Cohort: Research Resource for Environmental EpidemiologyR24ES028527 · NIEHS · UNIVERSITY OF CINCINNATI · PI PINNEY, SUSAN MENGEL · 2018 to 2024
$2.0M
Extreme Exposure Biomarker Levels: Guidance for InvestigatorsR13ES027347 · NIEHS · UNIVERSITY OF CINCINNATI · PI NEWMAN, NICHOLAS C, PINNEY, SUSAN MENGEL · 2017 to 2017
$8k
NIEHS NIH HHS P30 ES006096NIEHS NIH HHS R13 ES027347NIEHS NIH HHS R24 ES028527
6 · The paper itself

Abstract

purposeMembers of the American College of Epidemiology (ACE) Ethics Committee identified current ethics and epidemiology topic areas to consider for further discussion, consultation, teaching opportunities, and conference presentation. This article reflects on the activities of the Committee at the ACE Annual Meeting in New Orleans, Louisiana, September 24-26, 2017.

methodsThe overall aim for the Ethics Committee was to engage members of the College and other audiences and highlight the evolution of ethics and epidemiology since the inception of the original Ethics Guidelines published by the ACE Ethics and Standards of Practice Committee in 2000. The Ethics Committee organized a symposium session at the 2017 Annual Meeting of ACE on the ethics of human subjects research as it relates to specialized areas of epidemiology and the intersecting role of public health. This article presents a summary and further discussion of that symposium session.

resultsThree topic areas were presented: an overview of ethics and epidemiology (E.S.P.), very high biomarker levels in environmental epidemiology research (S.M.P.), and the interface of epidemiology, human subjects research, and public health interventions (S.M.). This article begins by reviewing the foundations of epidemiology and public health and the well-known ethical principles of human subjects research. Then, it considers the ethical considerations in the use of population registry data in epidemiological research, environmental epidemiology, and epidemic surveillance and response. This article may form the basis of teaching of ethics principles related to epidemiology and public health and may serve as a companion piece to the original ACE Ethics Guidelines.

conclusionsResearchers are increasingly faced with ethical considerations in diverse, nontraditional, and specialized areas of epidemiology and public health. This article illustrates these challenges with real-world examples of clinical and population registry data, the study of environmental biomarkers, and Zika virus epidemic; it also reviews relevant ethical principles underpinning these examples and identifies where gaps in knowledge may exist.

Indexed as

Ethics CommitteesResearch SubjectsEpidemiologyEthics, MedicalHumansPublic HealthZika VirusZika Virus InfectionBiomarkersEpidemiologyEthicsInterventionsPopulation RegistriesPublic HealthZika virus

Identifiers

PMID31005553
PMCPMC7370238

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.