Evidence map›Paper›PMID 31005136›Full record

ReviewInfectious disease clinics of North America2019

Clostridioides difficile Infection in the Stem Cell Transplant and Hematologic Malignancy Population.

Elizabeth Ann Misch, Nasia Safdar

Abstract readReview
In one paragraph

Review in Infectious disease clinics of North America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Evaluation of Primary Oral Vancomycin Prophylaxis AgainstOpen forum infectious diseases · 2024
    Article
  4. Review
  5. Review
  6. Effectiveness of oral vancomycin as prophylaxis againstAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  7. Article
  8. Journal of clinical medicine · 2022
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elizabeth Ann MischDepartment of Medicine, Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, 1685 Highland Drive, Centennial Building, 5th Floor, Madison, WI 53705, USA. Electronic address: eamisch@medicine.wisc.edu.
Nasia SafdarDepartment of Medicine, Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, 1685 Highland Drive, Centennial Building, 5th Floor, Madison, WI 53705, USA; Department of Medicine, William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA.
University of Wisconsin–Madison · US

Funding

Fecal Microbiota Transplant for C. difficile Infection in Solid Organ Transplant RecipientsU01AI125053 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SAFDAR, NASIA · 2018 to 2022
$5.2M
Fluoroquinolone Restriction for the Prevention of C. difficile Infection (CDI)_the FIRST Trial.R01HS026226 · AHRQ · UNIVERSITY OF WISCONSIN-MADISON · PI SAFDAR, NASIA · 2018 to 2022
$2.5M
Efficacy of oral vancomycin prophylaxis for prevention of recurrent C. difficile infectionR01HS025713 · AHRQ · UNIVERSITY OF WISCONSIN-MADISON · PI SAFDAR, NASIA · 2017 to 2021
$2.4M
Modelling applications and systems engineering to reduce infections_the MASTERI study.DP2AI144244 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SAFDAR, NASIA · 2018 to 2018
$2.3M
AHRQ HHS R01 HS025713AHRQ HHS R01 HS026226NIAID NIH HHS DP2 AI144244NIAID NIH HHS U01 AI125053
6 · The paper itself

Abstract

Clostridioides difficile infection (CDI) is common in the stem cell transplant (SCT) and hematologic malignancy (HM) population and mostly occurs in the early posttransplant period. Treatment of CDI in SCT/HM is the same as for the general population, with the exception that fecal microbiota transplant (FMT) has not been widely adopted because of safety concerns. Several case reports, small series, and retrospective studies have shown that FMT is effective and safe. A randomized controlled trial of FMT for prophylaxis of CDI in SCT patients is underway. In addition, an abundance of novel therapeutics for CDI is currently in development.

Indexed as

Clostridioides difficileClostridium InfectionsDrug TherapyFecal Microbiota TransplantationFecesGraft vs Host DiseaseHematologic NeoplasmsHumansMicrobiotaRandomized Controlled Trials as TopicRisk FactorsStem Cell TransplantationTreatment OutcomeClostridioides (Clostridium) difficileGraft-versus-host diseaseHematologic malignancyStem cell transplant

Identifiers

PMID31005136
PMCPMC6790983
OpenAlexW2938286087

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.