Evidence map›Paper›PMID 31004424›Full record

SynthesisMedical science monitor : international medical journal of experimental and clinical research2019

The Clinical Effectiveness of Calcium Hydroxide in Root Canal Disinfection of Primary Teeth: A Meta-Analysis.

Liying Jia, Xiaolin Zhang, Hong Shi, Ting Li, Bingjian Lv, Meng Xie

RetractedOpen access · hybridAbstract readMeta-AnalysisRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Medical science monitor : international medical journal of experimental and clinical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Retracted: The Clinical Effectiveness of Calcium Hydroxide in Root Canal Disinfection of Primary Teeth: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  3. Article
  4. Article
  5. Harnessing biomolecules for bioinspired dental biomaterials.Journal of materials chemistry. B · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Liying JiaDepartment of Pediatric Dentistry, Hospital of Stomatology Hebei Medical University, Shijiazhuang, Hebei, China (mainland).
Xiaolin ZhangDepartment of Epidemiology and Statistics, School of Public Health, Hebei Medical University, Shijiazhuang, Hebei, China (mainland).
Hong ShiDepartment of Pediatric Dentistry, Hospital of Stomatology Hebei Medical University, Shijiazhuang, Hebei, China (mainland).
Ting LiDepartment of Pathology, Hospital of Stomatology Hebei Medical University, Shijiazhuang, Hebei, China (mainland).
Bingjian LvDepartment of Pediatric Dentistry, Hospital of Stomatology Hebei Medical University, Shijiazhuang, Hebei, China (mainland).
Meng XieDepartment of Pediatric Dentistry, Hospital of Stomatology Hebei Medical University, Shijiazhuang, Hebei, China (mainland).
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND The aim of this research was to systematically analyze the effectiveness of calcium hydroxide compared to formocresol (FC) and camphor phenol (CP) in root canal disinfection of primary teeth. MATERIAL AND METHODS The meta-analysis was based on the participants, interventions, control, outcome (PICO) study design principle and 16 randomized-controlled clinical trials published from January 2000 to August 2018. The data heterogeneity of each study was assessed by the Q-test. The odds ratio and 95% confidence interval (CI) were calculated based on the heterogeneity results by Revman software. RESULTS Sixteen randomized-controlled clinical trials of 3047 primary teeth were included in this meta-analysis. There were significant differences of clinical effectiveness between calcium hydroxide and FC in root canal disinfection of primary teeth (OR=3.37; 95% CI range: 2.54-4.48, P<0.01) and endodontic inter-appointment emergencies (EIAE) after disinfection for 7 days (OR=0.26; 95% CI range: 0.16-0.42, P<0.01). However, there was no statistical difference of EIAE, after disinfection of primary teeth for 48 hours, between calcium hydroxide and FC (OR=0.62; 95% CI range: 0.34-1.11, P=0.11). There were significant differences of clinical effectiveness between the calcium hydroxide and CP in root canal disinfection of primary teeth (OR=5.50; 95% CI range: 3.36-8.98, P<0.01). CONCLUSIONS This meta-analysis indicated that the effectiveness of calcium hydroxide as root canal disinfectant in primary teeth was more effective than that of FC and CP.

Indexed as

Calcium HydroxideCamphorDental DisinfectantsDental Pulp CavityDrug CombinationsFormocresolsHumansPhenolsRandomized Controlled Trials as TopicRoot Canal TherapyTooth, DeciduousTreatment OutcomeCalcium HydroxideCamphorcamphorated phenolDental DisinfectantsDrug CombinationsformocresolFormocresolsPhenols

Identifiers

PMID31004424
PMCPMC6487674
OpenAlexW2938523018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.