Evidence map›Paper›PMID 31004413›Full record

ArticleBrain and behavior2019

Neural substrates of self- and external-preoccupation: A voxel-based morphometry study.

Shigeyuki Ikeda, Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Ryoichi Yokoyama, Seishu Nakagawa, Atsushi Sekiguchi, Kunio Iizuka, Sugiko Hanawa, Tsuyoshi Araki and 6 more

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Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Shigeyuki IkedaDepartment of Ubiquitous Sensing, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.ORCID 0000-0001-8175-6966
Hikaru TakeuchiDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Yasuyuki TakiDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Rui NouchiSmart Aging Research Center, Tohoku University, Sendai, Japan.
Ryoichi YokoyamaDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Seishu NakagawaDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Atsushi SekiguchiDepartment of Advanced Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Kunio IizukaDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Sugiko HanawaDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Tsuyoshi ArakiDepartment of Advanced Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Carlos Makoto MiyauchiDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Kohei SakakiDepartment of Advanced Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Takayuki NozawaDepartment of Ubiquitous Sensing, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Susumu YokotaDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Daniele MagistroDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Ryuta KawashimaDepartment of Ubiquitous Sensing, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSelf- and external-preoccupation have been linked to psychopathological states. The neural substrates underlying self- and external-preoccupation remain unclear. In the present study, we aim to provide insight into the information-processing mechanisms associated with self- and external-preoccupation at the structural level.

methodsTo investigate the neural substrates of self- and external-preoccupation, we acquired high-resolution T1-weighted structural images and Preoccupation Scale scores from 1,122 young subjects. Associations between regional gray matter volume (rGMV) and Preoccupation Scale subscores for self- and external-preoccupation were estimated using voxel-based morphometry.

resultsSignificant positive associations between self-preoccupation and rGMV were observed in widespread brain areas such as the bilateral precuneus and posterior cingulate gyri, structures known to be associated with self-triggered self-reference during rest. Significant negative associations between external-preoccupation and rGMV were observed only in the bilateral cerebellum, regions known to be associated with behavioral addiction, sustained attention, and reward system.

conclusionOur results reveal distinct neural substrates for self- and external-preoccupation at the structural level.

Indexed as

AdolescentAdultBrainBrain MappingEgoFemaleGray MatterHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleRestYoung Adultcerebellumgray matter volumemagnetic resonance imagingposterior cingulate cortexprecuneusPreoccupation Scale

Identifiers

PMID31004413
PMCPMC6576210

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.