Evidence map›Paper›PMID 31004383›Full record

ArticleJournal of veterinary internal medicine2019

Successful management of 3 dogs with colonic pythiosis using itraconzaole, terbinafine, and prednisone.

Krystle L Reagan, Stanley L Marks, Patricia A Pesavento, Ann Della Maggiore, Bing Y Zhu, Amy M Grooters

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Colorectal basidiobolomycosis in a dog.Journal of veterinary internal medicine · 2020
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Krystle L ReaganVeterinary Medical Teaching Hospital, University of California Davis, Davis, California.ORCID https://orcid.org/0000-0003-3426-6352
Stanley L MarksDepartment of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California.ORCID https://orcid.org/0000-0001-7991-702X
Patricia A PesaventoDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, California.
Ann Della MaggioreVeterinary Medical Teaching Hospital, University of California Davis, Davis, California.
Bing Y ZhuVeterinary Medical Teaching Hospital, University of California Davis, Davis, California.
Amy M GrootersDepartment of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana.
Veterinary Medical Teaching Hospital · USUniversity of California, Davis · USLouisiana State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal (GI) pythiosis is a severe and often fatal disease in dogs that traditionally has been poorly responsive to medical treatment. Although aggressive surgical resection with wide margins is the most consistently effective treatment, lesion location and extent often preclude complete resection. Recently, it has been suggested that the addition of anti-inflammatory doses of corticosteroids may improve outcome in dogs with nonresectable GI pythiosis. This report describes 3 dogs with colonic pythiosis in which complete resolution of clinical signs, regression of colonic masses, and progressive decreases in serological titers were observed after treatment with itraconazole, terbinafine, and corticosteroids. This treatment protocol represents a promising treatment for dogs with GI pythiosis in which surgical intervention is not feasible.

Indexed as

AnimalsAntifungal AgentsAnti-Inflammatory AgentsColonDog DiseasesDogsGastrointestinal DiseasesItraconazolePrednisonePythiosisPythiumSerologic TestsTerbinafineAntifungal AgentsAnti-Inflammatory AgentsItraconazolePrednisoneTerbinafineantifungalcolitisoomycetePythium insidiosum

Identifiers

PMID31004383
PMCPMC6524395
OpenAlexW2936399074

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.