ArticleActa neurochirurgica2019
Manual for clinical language tractography.
Article in Acta neurochirurgica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neural pathway-guided radiosurgery: A systematic review and meta-analysis of diffusion tensor imaging applications in stereotactic radiosurgery.Neurosurgical review · 2026Pooled it
- From cortical and white matter structure to meaning: a brain-constrained neural network of semantic grounding in action and perception.Frontiers in human neuroscience · 2026Article
- Quality and efficiency of a semi-automatic anatomy-based method for tractography of associative white matter fascicles in brain tumor patients, a case series.Neurosurgical review · 2025Article
- Quantitative evaluation of neuroradiological and morphometric alteration of inferior Fronto-Occipital Fascicle across different brain tumor histotype: an Italian multicentric study.Acta neurochirurgica · 2025Article
- Translational network neuroscience: Nine roadblocks and possible solutions.Network neuroscience (Cambridge, Mass.) · 2025Article
- Recovery of Verbal Working Memory Depends on Left Hemisphere White Matter Tracts.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Function-guided differences of arcuate fascicle and inferior fronto-occipital fascicle tractography as diagnostic indicators for surgical risk stratification.Brain structure & function · 2024Article
- Preoperative mapping techniques for brain tumor surgery: a systematic review.Frontiers in oncology · 2024Review
- Mapping action naming in patients with gliomas: The influence of transitivity.Neuroimage. Reports · 2023Article
- Improved prediction of glioma-related aphasia by diffusion MRI metrics, machine learning, and automated fiber bundle segmentation.Human brain mapping · 2023Article
- Structural connectivity in ventral language pathways characterizes non-verbal autism.Brain structure & function · 2022Article
- Tractography-based navigated TMS language mapping protocol.Frontiers in oncology · 2022Article
- Review
- Article
- Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?NeuroImage · 2021Article
- The Relevant Role of Navigated Tractography in Speech Eloquent Area Glioma Surgery: Single Center Experience.Brain sciences · 2021Article
- Effects of tDCS on Language Recovery in Post-Stroke Aphasia: A Pilot Study Investigating Clinical Parameters and White Matter Change with Diffusion Imaging.Brain sciences · 2021Article
- Preoperative Repetitive Navigated TMS and Functional White Matter Tractography in a Bilingual Patient with a Brain Tumor in Wernike Area.Brain sciences · 2021Article
- Middle Frontal Gyrus and Area 55b: Perioperative Mapping and Language Outcomes.Frontiers in neurology · 2021Article
- Preoperative nTMS and Intraoperative Neurophysiology - A Comparative Analysis in Patients With Motor-Eloquent Glioma.Frontiers in oncology · 2021Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundWe introduce a user-friendly, standardized protocol for tractography of the major language fiber bundles.
methodThe introduced method uses dMRI images for tractography whereas the ROI definition is based on structural T1 MPRAGE MRI templates, without normalization to MNI space. ROIs for five language-relevant fiber bundles were visualized on an axial, coronal, or sagittal view of T1 MPRAGE images. The ROIs were defined based upon the tracts' obligatory pathways, derived from literature and own experiences in peritumoral tractography.
resultsThe resulting guideline was evaluated for each fiber bundle in ten healthy subjects and ten patients by one expert and three raters. Overall, 300 ROIs were evaluated and compared. The targeted language fiber bundles could be tracked in 88% of the ROI pairs, based on the raters' result blinded ROI placements. The evaluation indicated that the precision of the ROIs did not relate to the varying experience of the raters.
conclusionsOur guideline introduces a standardized language tractography method for routine preoperative workup and for research contexts. The ROI placement guideline based on easy-to-identify anatomical landmarks proved to be user-friendly and accurate, also in inexperienced test persons.
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