Evidence map›Paper›PMID 31004106›Full record

ArticleScientific reports2019

Anthropogenic Effects on Natural Mammalian Populations: Correlation Between Telomere Length and Coal Exposure.

Cristina A Matzenbacher, Juliana Da Silva, Ana Leticia H Garcia, Mónica Cappetta, Thales R O de Freitas

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Cristina A MatzenbacherDepartment of Genetics, Federal University of Rio Grande do Sul, C.P. 15053, 91501-970, Porto Alegre, RS, Brazil.ORCID http://orcid.org/0000-0001-7022-2483
Juliana Da SilvaLaboratory of Genetic Toxicology, Lutheran University of Brazil, ULBRA, Canoas, 92425-900, Rio Grande do Sul, Brazil. juliana.silva@ulbra.br.ORCID http://orcid.org/0000-0002-1089-6766
Ana Leticia H GarciaLaboratory of Genetic Toxicology, Lutheran University of Brazil, ULBRA, Canoas, 92425-900, Rio Grande do Sul, Brazil.
Mónica CappettaLaboratorio de Epidemiología Genética, Departamento de Genética, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.ORCID http://orcid.org/0000-0003-2015-0156
Thales R O de FreitasDepartment of Genetics, Federal University of Rio Grande do Sul, C.P. 15053, 91501-970, Porto Alegre, RS, Brazil.
Universidade Federal do Rio Grande do Sul · BRUniversidad de la República de Uruguay · UYUniversidade Feevale · BRUniversidade Luterana do Brasil · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Candiota coal mine in Rio Grande do Sul (RS) is one of the largest in Brazil. Coal is a fossil fuel that causes environmental impacts from its extraction to combustion due to the release of different agents, such as polycyclic aromatic hydrocarbons (PAH) and heavy metals. Ctenomys torquatus are herbivorous and subterranean rodents that dig tunnels with their paws and teeth and can be exposed to coal through contaminated food. Exposure to pollutants can cause DNA damage and affect different tissues, inducing alterations in the population structure and genetic diversity. Our study aimed to evaluate the effect of exposure to coal and its derivatives on the C. torquatus population and to examine the relationship of coal exposure with variations in absolute telomere length (aTL), global DNA methylation and genotoxicity. Our study showed an inverse correlation between telomere length and coal exposure in addition to an increase in DNA damage. The results indicate that coal and its byproducts can contribute to the alteration of the C. torquatus population structure, as evidenced by a reduction in the number of adults.

Indexed as

Coal MiningRodentiaAnimalsCoalDNA DamageHumansPopulation DynamicsTelomere HomeostasisCoal

Identifiers

PMID31004106
PMCPMC6474877
OpenAlexW2936573618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.