Evidence map›Paper›PMID 31004034›Full record

ArticleHaematologica2019

Identification of candidate nonsense mutations of FVIII for ribosomal readthrough therapy.

Zhigang Liu, Yuan Zhang, Min Zhu, Bin Zhang

Abstract readLetter
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhigang LiuGenomic Medicine Institute, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA and.
Yuan ZhangGenomic Medicine Institute, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA and.
Min ZhuGenomic Medicine Institute, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA and zhumkaramay@163.com.com.
Bin ZhangGenomic Medicine Institute, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA and zhangb@ccf.org.

Funding

ER-to-Golgi transport of coagulation factors V and VIIIR01HL094505 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI ZHANG, BIN · 2009 to 2022
$5.1M
LMAN1 mutations in colorectal cancer developmentR03CA202131 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI ZHANG, BIN · 2017 to 2018
$159k
NCI NIH HHS R03 CA202131NHLBI NIH HHS R01 HL094505
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Codon, NonsenseFactor VIIIHEK293 CellsHemophilia BHumansProtein BiosynthesisRibosomesSmall Molecule LibrariesCodon, NonsenseF8 protein, humanFactor VIIISmall Molecule Libraries

Identifiers

PMID31004034
PMCPMC6959177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.