Evidence map›Paper›PMID 31003512›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Trastuzumab-Modified Gold Nanoparticles Labeled with

Łucja Dziawer, Agnieszka Majkowska-Pilip, Damian Gaweł, Marlena Godlewska, Marek Pruszyński, Jerzy Jastrzębski, Bogdan Wąs, Aleksander Bilewicz

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Targeted photodynamic therapy for MCF-7 breast cancer using antibody-conjugated, green-synthesized gold nanoparticles loaded with hypericin: a proof of concept.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Small science · 2025
    Review
  8. Materials (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. Au@EJNMMI radiopharmacy and chemistry · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Łucja DziawerCentre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland. l.janiszewska@ichtj.waw.pl.
Agnieszka Majkowska-PilipCentre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland. a.majkowska@ichtj.waw.pl.ORCID 0000-0001-9449-6411
Damian GawełDepartment of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland. damian.gawel@cmkp.edu.pl.ORCID 0000-0002-1270-5505
Marlena GodlewskaDepartment of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland. marlena.godlewska@cmkp.edu.pl.ORCID 0000-0003-2337-6724
Marek PruszyńskiCentre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland. m.pruszynski@ichtj.waw.pl.ORCID 0000-0001-8835-2462
Jerzy JastrzębskiHeavy Ion Laboratory, University of Warsaw, Pasteura 5A, 02-093 Warsaw, Poland. jastj@slcj.uw.edu.pl.
Bogdan WąsInstitute of Nuclear Physics, Polish Academy of Sciences, Radzikowskiego 152, 31-342 Cracow, Poland. Bogdan.Was@ifj.edu.pl.
Aleksander BilewiczCentre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland. a.bilewicz@ichtj.waw.pl.
Instytut Chemii i Techniki Jądrowej · PLPostgraduate School of Molecular Medicine · PLInstitute of Nuclear Physics, Polish Academy of Sciences · PLUniversity of Warsaw · PL

Funding

National Science Centre of Poland 2013/11/B/ST4/00516
6 · The paper itself

Abstract

Highly localized radiotherapy with radionuclides is a commonly used treatment modality for patients with unresectable solid tumors. Herein, we propose a novel α-nanobrachytherapy approach for selective therapy of human epidermal growth factor receptor 2 (HER2)-positive breast cancer. This uses local intratumoral injection of 5-nm-diameter gold nanoparticles (AuNPs) labeled with an α-emitter (

Indexed as

HER2 receptormonoclonal antibodySKOV-3 ovarian cell lineα-emitter 211Atα-nanobrachytherapy

Identifiers

PMID31003512
PMCPMC6523862
OpenAlexW2938140328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.