ArticleContemporary clinical trials2019
Randomized trial evaluating the role of weight loss in overweight and obese men with early stage prostate Cancer on active surveillance: Rationale and design of the Prostate Cancer Active Lifestyle Study (PALS).
Article in Contemporary clinical trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recommendations on Weight Loss and Healthy Lifestyle in Prostate Cancer Clinical Guidelines: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Reduced adipose tissue with limited loss of lean mass after weight loss: results from the Prostate Cancer Active Lifestyle Study.Journal of the National Cancer Institute · 2025Trial
- Trial
- A Problem in NIH and Federally Funded Prostate Cancer Interventional Clinical Trials.Journal of racial and ethnic health disparities · 2024Article
- Body mass index and survival among patients with advanced biliary tract cancer: a single-institutional study with nationwide data-based validation.Journal of gastroenterology · 2024Article
- The impact of a fasting mimicking diet on the metabolic health of a prospective cohort of patients with prostate cancer: a pilot implementation study.Prostate cancer and prostatic diseases · 2023Article
- Physical Inactivity, Metabolic Syndrome and Prostate Cancer Diagnosis: Development of a Predicting Nomogram.Metabolites · 2023Article
- Improving physical activity among prostate cancer survivors through a peer-based digital walking program.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2023Article
- An Intervention Offering Self-management Support Through mHealth and Health Coaching to Patients With Prostate Cancer: Interpretive Description of Patients' Experiences and Perspectives.JMIR formative research · 2022Article
- Metabolic Syndrome and Physical Inactivity May Be Shared Etiological Agents of Prostate Cancer and Coronary Heart Diseases.Cancers · 2022Article
- Physical activity decreases the risk of cancer reclassification in patients on active surveillance: a multicenter retrospective study.Prostate cancer and prostatic diseases · 2021Article
- Review
- Round up.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
- Impact of lifestyle in prostate cancer patients. What should we do?International braz j urol : official journal of the Brazilian Society of UrologyReview
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Active surveillance (AS) is increasingly used to monitor patients with low-risk prostate cancer; however, approximately 50% of AS patients experience disease reclassification requiring definitive treatment and little is known about patient characteristics that modify the risk of reclassification. Obesity may be one of the major contributing factors. The Prostate Cancer Active Lifestyle Study (PALS) is a clinical trial evaluating the impact of weight loss among overweight/obese (Body Mass Index (BMI) ≥ 25 kg/m
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.