Evidence map›Paper›PMID 31002954›Full record

Trial reportJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2019

Prakash Manoharan, Ahmed Salem, Hitesh Mistry, Michael Gornall, Susan Harden, Peter Julyan, Imogen Locke, Jonathan McAleese, Rhona McMenemin, Nazia Mohammed and 4 more

Open access · hybridAbstract readClinical Trial, Phase IIIRandomized Controlled Trial
In one paragraph

Trial report in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-upAnnals of oncology : official journal of the European Society for Medical Oncology · 2021
    Guideline
  2. Impact ofFrontiers in medicine · 2019
    Pooled it
  3. Pooled it
  4. Evaluating the prognostic impact of multipleEuropean journal of nuclear medicine and molecular imaging · 2026
    Trial
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. GOECP/SEOR radiotherapy guidelines for small-cell lung cancer.World journal of clinical oncology · 2021
    Review
  12. Current and future strategies in radiotherapy for small-cell lung cancer.Journal of clinical and translational research · 2020
    Review
  13. Recent advances of PET imaging in clinical radiation oncology.Radiation oncology (London, England) · 2020
    Review
  14. Recent developments in limited stage small cell lung cancer.Translational lung cancer research · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Prakash ManoharanDepartment of Radiology, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Department of Nuclear Medicine, The Christie National Health Service Foundation Trust, Manchester, United Kingdom. Electronic address: prakash.manoharan@christie.nhs.uk.
Ahmed SalemDivision of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Department of Clinical Oncology, The Christie National Health Service Foundation Trust, Manchester, United Kingdom.
Hitesh MistryDivision of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Division of Pharmacy, University of Manchester, Manchester, United Kingdom.
Michael GornallDepartment of Nuclear Medicine, The Christie National Health Service Foundation Trust, Manchester, United Kingdom.
Susan HardenDepartment of Clinical Oncology, Addenbrooke's Hospital, Cambridge, United Kingdom.
Peter JulyanDepartment of Nuclear Medicine, The Christie National Health Service Foundation Trust, Manchester, United Kingdom.
Imogen LockeDepartment of Clinical Oncology, The Royal Marsden National Health Service Foundation Trust, Surrey, United Kingdom.
Jonathan McAleeseDepartment of Clinical Oncology, Northern Ireland Cancer Centre, Belfast City Hospital, Belfast, United Kingdom.
Rhona McMeneminDepartment of Clinical Oncology, Northern Centre for Cancer Care, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom.
Nazia MohammedDepartment of Clinical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom.
Michael SneeDepartment of Clinical Oncology, Leeds Cancer Centre, St James's Hospital, Leeds, United Kingdom.
Sarah WoodsDepartment of Nuclear Medicine, Manchester University National Health Service Foundation Trust, Manchester, United Kingdom.
Thomas WestwoodDepartment of Radiology, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Department of Nuclear Medicine, The Christie National Health Service Foundation Trust, Manchester, United Kingdom.
Corinne Faivre-FinnDivision of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Department of Clinical Oncology, The Christie National Health Service Foundation Trust, Manchester, United Kingdom.
National Health Service · GBThe Christie NHS Foundation Trust · GBAddenbrooke's Hospital · GBBeatson West of Scotland Cancer Centre · GBFreeman Hospital · GBSt James's University Hospital · GBThe Northern Ireland Cancer Centre · GBUniversity of Manchester · GB

Funding

Cancer Research UK 18097Cancer Research UK 8154
6 · The paper itself

Abstract

introductionWe used phase-3 CONVERT trial data to investigate the impact of fludeoxyglucose F 18 (

methodsCONVERT randomized patients with limited-stage SCLC to twice-daily (45 Gy in 30 fractions) or once-daily (66 Gy in 33 fractions) chemoradiotherapy. Patients were divided into two groups in this unplanned analysis: those staged with conventional imaging (contrast-enhanced thorax and abdomen CT and brain imaging with or without bone scintigraphy) and those staged with

resultsData on a total of 540 patients were analyzed. Compared with patients who underwent conventional imaging (n = 231), patients also staged with

conclusionIn CONVERT, survival outcomes were not significantly different in patients staged with or without

Indexed as

Fluorodeoxyglucose F18RadiopharmaceuticalsAdultAgedAged, 80 and overChemoradiotherapyFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedPositron Emission Tomography Computed TomographyPrognosisSmall Cell Lung CarcinomaSurvival RateFluorodeoxyglucose F18Radiopharmaceuticals(18)F-FDG PET/CTlung cancersmall-cellstagingsurvival

Identifiers

PMID31002954
PMCPMC6616906
OpenAlexW2939133296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.