Evidence map›Paper›PMID 31002725›Full record

ArticlePloS one2019

Markerless motion tracking and correction for PET, MRI, and simultaneous PET/MRI.

Jakob M Slipsager, Andreas H Ellegaard, Stefan L Glimberg, Rasmus R Paulsen, M Dylan Tisdall, Paul Wighton, André van der Kouwe, Lisbeth Marner, Otto M Henriksen, Ian Law and 1 more

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Fast Reconstruction for Deep Learning PET Head Motion Correction.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2023
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  20. Synergistic motion compensation strategies for positron emission tomography when acquired simultaneously with magnetic resonance imaging.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jakob M SlipsagerDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0003-0040-9730
Andreas H EllegaardDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0002-1463-2223
Stefan L GlimbergTracInnovations, Ballerup, Denmark.
Rasmus R PaulsenDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark.
M Dylan TisdallRadiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Paul WightonAthinoula. A. Matinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
André van der KouweAthinoula. A. Matinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Lisbeth MarnerDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Otto M HenriksenDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Ian LawDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-9644-7496
Oline V OlesenDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0001-6392-4444

Funding

Longitudinal Neuroimaging and Cognitive Study of HIV-Infected ChildrenR01HD071664 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI LAUGHTON, BARBARA, MEINTJES, ERNESTA MARIA · 2011 to 2015
$2.4M
High-Speed Motion-Corrected Pediatric Neuroimaging with MRIR00HD074649 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI TISDALL, MATTHEW DYLAN · 2015 to 2017
$706k
NICHD NIH HHS R00 HD074649NICHD NIH HHS R01 HD071664
6 · The paper itself

Abstract

objectiveWe demonstrate and evaluate the first markerless motion tracker compatible with PET, MRI, and simultaneous PET/MRI systems for motion correction (MC) of brain imaging.

methodsPET and MRI compatibility is achieved by careful positioning of in-bore vision extenders and by placing all electronic components out-of-bore. The motion tracker is demonstrated in a clinical setup during a pediatric PET/MRI study including 94 pediatric patient scans. PET MC is presented for two of these scans using a customized version of the Multiple Acquisition Frame method. Prospective MC of MRI acquisition of two healthy subjects is demonstrated using a motion-aware MRI sequence. Real-time motion estimates are accompanied with a tracking validity parameter to improve tracking reliability.

resultsFor both modalities, MC shows that motion induced artifacts are noticeably reduced and that motion estimates are sufficiently accurate to capture motion ranging from small respiratory motion to large intentional motion. In the PET/MRI study, a time-activity curve analysis shows image improvements for a patient performing head movements corresponding to a tumor motion of ±5-10 mm with a 19% maximal difference in standardized uptake value before and after MC.

conclusionThe first markerless motion tracker is successfully demonstrated for prospective MC in MRI and MC in PET with good tracking validity. SIGNIFICANCE: As simultaneous PET/MRI systems have become available for clinical use, an increasing demand for accurate motion tracking and MC in PET/MRI scans has emerged. The presented markerless motion tracker facilitate this demand.

Indexed as

BrainChildHead MovementsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMotionMultimodal ImagingNeoplasmsPositron-Emission TomographyProspective StudiesReproducibility of Results

Identifiers

PMID31002725
PMCPMC6474595

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.