SynthesisPloS one2019
Epidemiology of tuberculous lymphadenitis in Africa: A systematic review and meta-analysis.
Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Knowledge of reproductive-age women about mother-to-child transmission of HIV and associated factors: a systematic review and meta-analysis.Systematic reviews · 2026Pooled it
- Retention in Care After Transition to Adult Care for Adolescents and Young Adults With HIV: A Systematic Review and Meta-Analysis.International journal of public health · 2025Pooled it
- Pooled it
- Efficacy and tolerability of a 4-month ofloxacin-containing regimen compared to a 6-month regimen in the treatment of patients with superficial lymph node tuberculosis: a randomized trial.BMC infectious diseases · 2024Trial
- Clinical spectrum of extrapulmonary tuberculosis at a tertiary care centre in Ghana: a retrospective study.BMC infectious diseases · 2026Article
- Ultrasound-guided lymph node biopsies: feasible and safe use of pathology services in a resource-limited, high TB/HIV prevalence setting.The ultrasound journal · 2026Article
- Health and Economic Burden of Rabies in Northwest Ethiopia.PharmacoEconomics - open · 2025Article
- A clinical scoring system to predict tuberculous lymphadenitis in settings with high disease burden.Scientific reports · 2025Article
- Extrapulmonary Comparisons BetweenInfection and drug resistance · 2025Review
- Factors predicting outcome in cervical lymph node tuberculosis: insights from a Tunisian case series.F1000Research · 2025Article
- Identifying risk factors for recurrent multidrug resistant tuberculosis based on patient's record data from 2016 to 2021: retrospective study.Scientific reports · 2024Article
- Magnitude of tuberculosis lymphadenitis, risk factors, and rifampicin resistance at Adama city, Ethiopia: a cross-sectional study.Scientific reports · 2023Article
- Comparative serum lipid and immunohematological values among adult pulmonary tuberculosis and tuberculosis lymphadenitis cases and their association with sputum bacilli load and time to culture positivity in Northwestern Ethiopia.Lipids in health and disease · 2023Article
- More thanThorax · 2023Article
- Comparative whole-genome sequence analysis ofFrontiers in microbiology · 2023Article
- Evaluation of modified bleach technique for the detection of acid fast bacilli in lymph node aspirate at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.Journal of clinical tuberculosis and other mycobacterial diseases · 2022Article
- Profile and histopathology features of top three cases of Extra Pulmonary Tuberculosis (EPTB) in West Nusa Tenggara: A retrospective cross-sectional study.Annals of medicine and surgery (2012) · 2022Article
- Comparison of the Accuracy of Two Different Molecular Tests for the Diagnosis of Tuberculous Lymphadenitis Using Core Needle Biopsy Specimens: A Diagnostic Accuracy Study.International journal of general medicine · 2022Article
- Integration of cytopathology with molecular tests to improve the lab diagnosis for TBLN suspected patients.PloS one · 2022Article
- Feasibility and long-term safety of Ho:YAG laser lithotripsy in broncholithiasis patients.BMC pulmonary medicine · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTuberculous lymphadenitis is the most frequent form of extra-pulmonary TB (EPTB) and accounts for a considerable proportion of all EPTB cases. We conducted a systematic review of articles that described the epidemiological features of TBLN in Africa.
methodsAny article that characterized TBLN cases with respect to demographic, exposure and clinical features were included. Article search was restricted to African countries and those published in English language irrespective of publication year. The articles were retrieved from the electronic database of PubMed, Scopus, Cochrane library and Lens.org. Random effect pooled prevalence with 95% CI was computed based on Dersimonian and Laird method. To stabilize the variance, Freeman-Tukey double arcsine root transformation was done. The data were analyzed using Stata 14.
resultsOf the total 833 articles retrieved, twenty-eight articles from 12 African countries fulfilled the eligibility criteria. A total of 6746 TBLN cases were identified. The majority of the cases, 4762 (70.6%) were from Ethiopia. Over 77% and 88% of identified TBLN were cervical in type and naïve to TB drugs. Among the total number of TBLN cases, 53% were female, 68% were in the age range of 15-44 years, 52% had a history of livestock exposure, 46% had a history of consuming raw milk/meat and 24% had history of BCG vaccination. The proportion of TBLN/HIV co-infection was much lower in Ethiopia (21%) than in other African countries (73%) and the overall African estimate (52%). Fever was recorded in 45%, night sweating in 55%, weight loss in 62% and cough for longer than two weeks in 32% of the TBLN cases.
conclusionsTBLN was more common in females than in males. The high prevalence of TBLN in Ethiopia did not show directional correlation with HIV. Population based prospective studies are warranted to better define the risk factors of TBLN in Africa.
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