Evidence map›Paper›PMID 31002638›Full record

ArticlePreventing chronic disease2019

Association Between Changes in Postpartum Weight and Waist Circumference and Changes in Cardiometabolic Risk Factors Among Women With Recent Gestational Diabetes.

Jacinda M Nicklas, Bernard A Rosner, Chloe A Zera, Ellen W Seely

Erratum issuedAbstract readComparative Study
In one paragraph

Article in Preventing chronic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jacinda M NicklasDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.
Bernard A RosnerChanning Division of Network Medicine, Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Chloe A ZeraDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Brigham and Women's Hospital Boston, Massachusetts.
Ellen W SeelyDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Research Training in Complementary and Integrative MedicineT32AT000051 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GLORIA Y YEH · 1999 to 2026
$10.2M
UCHSC: Building Interdisciplinary Research Careers in Women's HealthK12HD057022 · NICHD · UNIVERSITY OF COLORADO DENVER · PI REGENSTEINER, JUDITH G., SANTORO, NANETTE F. · 2007 to 2023
$8.5M
The Colorado Building Interdisciplinary Research Careers in Women's Health ProgramK12AR084226 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI JUDITH G. REGENSTEINER, Nanette F. Santoro · 2023 to 2026
$2.5M
Unique cardiovascular Risk Factors in Women Research and Mentoring ProgamK24HL096141 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SEELY, ELLEN W · 2010 to 2014
$997k
Iterative development and pilot testing of a mobile health intervention to increase postpartum weight loss in women at increased risk for cardiometabolic diseaseK23HL133604 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI NICKLAS, JACINDA MAWSON · 2016 to 2019
$769k
NCATS NIH HHS UL1 TR001102NCCIH NIH HHS T32 AT000051NHLBI NIH HHS K23 HL133604NHLBI NIH HHS K24 HL096141NIAMS NIH HHS K12 AR084226NICHD NIH HHS K12 HD057022
6 · The paper itself

Abstract

introductionWomen with gestational diabetes mellitus (GDM) have a 30% to 70% risk for developing type 2 diabetes and are at increased risk for cardiovascular disease. Little is known about how anthropometric changes in the first postpartum year modify cardiometabolic risk factors.

methodsWe randomly assigned women in the Balance After Baby study to an intervention group consisting of participation in a web-based lifestyle program or to a control group in which no program was offered. We measured weight, height, waist circumference, blood pressure, lipids, insulin, adiponectin, interleukin-6, and high-sensitivity C-reactive protein, and we conducted 2-hour oral glucose tolerance tests at 6 weeks, 6 months, and 12 months postpartum. We evaluated whether women assigned to the intervention had improved cardiometabolic risk markers compared with the control group. We then conducted a post-hoc analysis, pooling the 2 groups to compare changes in weight and waist circumference with changes in cardiometabolic risk factors.

resultsWomen in the intervention group did not significantly improve cardiometabolic risk markers compared with women in the control group. We noted a large overlap of weight change and change in waist circumference between groups. In our post-hoc analysis pooling groups, changes in diabetes and cardiovascular risk factors were significantly correlated with changes in weight and waist circumference. The strongest associations were observed for fasting insulin, HOMA, and fasting glucose.

conclusionAnthropometric changes in weight and waist circumference in women with recent GDM may affect cardiometabolic risk factors, even in the first postpartum year. Our study demonstrates the importance of the postpartum year as an opportunity to decrease future risk for diabetes and cardiovascular disease in women with a history of GDM.

Indexed as

Healthy LifestyleAdolescentAdultBody WeightBostonCardiovascular DiseasesDiabetes, GestationalFemaleFollow-Up StudiesHealth PromotionHumansInternet-Based InterventionMetabolic DiseasesMiddle AgedPostpartum PeriodPregnancy

Identifiers

PMID31002638
PMCPMC6513485

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.