Evidence map›Paper›PMID 31002438›Full record

ArticleAngewandte Chemie (International ed. in English)2019

Subcellular Duplex DNA and G-Quadruplex Interaction Profiling of a Hexagonal Pt

Olaya Domarco, Claudia Kieler, Christine Pirker, Carina Dinhof, Bernhard Englinger, Johannes M Reisecker, Gerald Timelthaler, Marcos D García, Carlos Peinador, Bernhard K Keppler and 2 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. FeChemical science · 2021
    Article
  8. Article
  9. Metal-Coordinated Supramolecular Self-Assemblies for Cancer Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Subcellular Duplex DNA and G-Quadruplex Interaction Profiling of a Hexagonal PtAngewandte Chemie (International ed. in English) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Olaya DomarcoUniversidade da Coruña, Departamento de Química y Centro de Investigacións Científicas Avanzadas, E-15071 A, Coruña, Spain.
Claudia KielerMedical University of Vienna, Department of Medicine I, Institute of Cancer Research and Comprehensive Cancer Center, Borschkegasse 8a, A-1090, Vienna, Austria.
Christine PirkerMedical University of Vienna, Department of Medicine I, Institute of Cancer Research and Comprehensive Cancer Center, Borschkegasse 8a, A-1090, Vienna, Austria.ORCID 0000-0001-7104-4404
Carina DinhofMedical University of Vienna, Department of Medicine I, Institute of Cancer Research and Comprehensive Cancer Center, Borschkegasse 8a, A-1090, Vienna, Austria.
Bernhard EnglingerMedical University of Vienna, Department of Medicine I, Institute of Cancer Research and Comprehensive Cancer Center, Borschkegasse 8a, A-1090, Vienna, Austria.
Johannes M ReiseckerMedical University of Vienna, Department of Medicine I, Institute of Cancer Research and Comprehensive Cancer Center, Borschkegasse 8a, A-1090, Vienna, Austria.
Gerald TimelthalerMedical University of Vienna, Department of Medicine I, Institute of Cancer Research and Comprehensive Cancer Center, Borschkegasse 8a, A-1090, Vienna, Austria.
Marcos D GarcíaUniversidade da Coruña, Departamento de Química y Centro de Investigacións Científicas Avanzadas, E-15071 A, Coruña, Spain.ORCID 0000-0002-3189-740X
Carlos PeinadorUniversidade da Coruña, Departamento de Química y Centro de Investigacións Científicas Avanzadas, E-15071 A, Coruña, Spain.ORCID 0000-0001-5823-6217
Bernhard K KepplerUniversity of Vienna, Institute of Inorganic Chemistry, Waehringerstrasse 42, A-1090, Vienna, Austria.ORCID 0000-0003-0877-1822
Walter BergerMedical University of Vienna, Department of Medicine I, Institute of Cancer Research and Comprehensive Cancer Center, Borschkegasse 8a, A-1090, Vienna, Austria.ORCID 0000-0003-0014-1658
Alessio TerenziUniversity of Vienna, Institute of Inorganic Chemistry, Waehringerstrasse 42, A-1090, Vienna, Austria.ORCID 0000-0001-9751-1373

Funding

Doktorand/inn/enprogramm der Österreichischen Akademie der Wissenschaften 24660Mahlke-Obermann Stiftung and the European Union's Seventh Framework Programme 609431Ministerio de Economía, Industria y Competitividad and FEDER CTQ2016-75629-P
6 · The paper itself

Abstract

Metal-driven self-assembly afforded a multitude of fascinating supramolecular coordination complexes (SCCs) with applications as catalysts, host-guest, and stimuli-responsive systems. However, the interest in the biological applications of SCCs is only starting to emerge and thorough characterization of their behavior in biological milieus is still lacking. Herein, we report on the synthesis and detailed in-cell tracking of a Pt

Indexed as

G-QuadruplexesCell Line, TumorDNAFibroblastsHumansKeratinocytesMCF-7 CellsModels, MolecularOrganoplatinum CompoundsSpectrophotometry, UltravioletDNAOrganoplatinum CompoundsG-quadruplexmetallacycleplatinumSCCsubcellular localization

Identifiers

PMID31002438
PMCPMC6563712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.