Evidence map›Paper›PMID 31002388›Full record

ArticleFEBS letters2019

A new Elf5

Snahlata Singh, Emily Elenio, Nicolae A Leu, Rose-Anne Romano, Andrew E Vaughan, Jennifer DeRiso, Kameswaran Surendran, Rumela Chakrabarti

Open access · bronzeAbstract read
In one paragraph

Article in FEBS letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Snahlata SinghDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Emily ElenioDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Nicolae A LeuDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Rose-Anne RomanoDepartment of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, NY, USA.
Andrew E VaughanDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jennifer DeRisoPediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, USA.
Kameswaran SurendranPediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, USA.
Rumela ChakrabartiDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-7720-9660
University of Pennsylvania · USSanford Research · USUniversity at Buffalo, State University of New York · US

Funding

Yeast 2 HybridP20GM103620 · NIGMS · SANFORD RESEARCH/USD · PI ROUX, KYLE J · 2013 to 2023
$24.2M
The Impact of PD-1 Inhibition on Immune-Response to ChemoradiotherapyP20GM103548 · NIGMS · SANFORD RESEARCH/USD · PI MISKIMINS, W KEITH · 2012 to 2020
$20.8M
Deciphering the function of DNp63 and MDSCs in tumor promotion and metastasis of TNBCsR01CA237243 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHAKRABARTI, RUMELA · 2019 to 2023
$1.8M
Molecular Regulators of Renal Collecting Duct Differentiation and MaintenanceR01DK106135 · NIDDK · SANFORD RESEARCH/USD · PI SURENDRAN, KAMESWARAN · 2016 to 2019
$1.5M
Probing the role of tumor suppressive functions of Elf5 in breast cancerK22CA193661 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHAKRABARTI, RUMELA · 2016 to 2018
$562k
NCI NIH HHS K22 CA193661NCI NIH HHS R01 CA237243NIDDK NIH HHS R01 DK106135NIGMS NIH HHS P20 GM103548NIGMS NIH HHS P20 GM103620
6 · The paper itself

Abstract

Elf5 is a transcription factor known to regulate critical developmental processes and has been shown to act as a tumour suppressor in multiple cancers. Elf5 knockout mice are embryonically lethal, limiting in vivo studies pertaining to its function. Moreover, haploinsufficiency of Elf5 limits the use of current mouse models to investigate adult tissue distribution of Elf5. Here, we successfully generated Elf5

Indexed as

Cell LineageMice, TransgenicModels, AnimalAnimalsChromosomes, Artificial, BacterialDNA-Binding ProteinsIntegrasesMiceMice, KnockoutTranscription FactorsCre recombinaseDNA-Binding ProteinsElf5 protein, mouseIntegrasesTranscription FactorsElf5 Cre ERT 2- GFPkidneylungmammary glandprostatesalivary gland

Identifiers

PMID31002388
PMCPMC6538489
OpenAlexW2938683518

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.