SynthesisThe Journal of antimicrobial chemotherapy2019
Factors associated with antibiotic prescribing for adults with acute conditions: an umbrella review across primary care and a systematic review focusing on primary dental care.
Synthesis in The Journal of antimicrobial chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Supervised toothbrushing programs: evaluating impact, barriers, and facilitators - a mixed-method umbrella review.Evidence-based dentistry · 2025Pooled it
- Do Systemic Antibiotics Offer Benefits to the Surgical Treatment of Peri-Implantitis? A Systematic Review With Meta-Analyses.Journal of clinical periodontology · 2025Pooled it
- A Systematic Review of Dental Antibiotic Stewardship Interventions.Community dentistry and oral epidemiology · 2025Pooled it
- Resident-, prescriber-, and facility-level factors associated with antibiotic use in long-term care facilities: a systematic review of quantitative studies.Antimicrobial resistance and infection control · 2024Pooled it
- Does the problem begin at the beginning? Medical students' knowledge and beliefs regarding antibiotics and resistance: a systematic review.Antimicrobial resistance and infection control · 2020Pooled it
- Antibiotic prescription practices in primary care in low- and middle-income countries: A systematic review and meta-analysis.PLoS medicine · 2020Pooled it
- Antibiotics after non-surgical root canals: National Dental Practice-Based Research Network findings.Journal of dentistry · 2026Article
- Knowledge, Attitudes, and Practices of Antibiotic Prescribing Among Arab Dental Students: A Cross-Sectional Study.International dental journal · 2026Article
- Residency Competency Assessments and Early-Career Primary Care Physicians' Antibiotic Prescribing.JAMA network open · 2026Article
- De-Implementing Low-Value Care in Dentistry: The Case for Choosing Wisely Campaigns.Community dentistry and oral epidemiology · 2026Article
- Interprofessional Perceptions and Collaboration Between Medicine and Dentistry in Croatia: A Qualitative Study of Faculty and Student Perspectives.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Antibiotic dispensing practices and determinants among informal healthcare providers in low- and middle-income countries: a mixed-methods scoping review.BMJ global health · 2026Article
- Article
- Knowledge, attitudes and practices regarding antibiotic prescribing by dentists: a qualitative study in Chile.Journal of public health (Oxford, England) · 2026Article
- Safety-constrained evaluation of antibacterial multicomponent borate glasses.Biomaterials and biosystems · 2026Article
- Doctor-related Knowledge, Attitudes and Practices (KAP) factors influencing antibiotic prescribing for urinary tract infections in primary care in Singapore: a cross-sectional study.BMC primary care · 2026Article
- From knowledge to practice: Antibiotic prescribing behaviors and antimicrobial stewardship awareness among Iraqi dental students.AIMS public health · 2026Article
- Appropriateness of antibiotic prescribing in dental practice: results of two clinical audits conducted at a university hospital.Frontiers in oral health · 2026Article
- Oral health, antimicrobial resistance and the need for interprofessional education.Frontiers in oral health · 2026Review
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
introductionOne way to slow the spread of resistant bacteria is by improved stewardship of antibiotics: using them more carefully and reducing the number of prescriptions. With an estimated 7%-10% of antibiotic prescriptions globally originating from dental practices and up to 80% prescribed unnecessarily, dentistry has an important role to play. To support the design of new stewardship interventions through knowledge transfer between contexts, this study aimed to identify factors associated with the decision to prescribe antibiotics to adults presenting with acute conditions across primary care (including dentistry).
methodsTwo reviews were undertaken: an umbrella review across primary healthcare and a systematic review in dentistry. Two authors independently selected and quality assessed the included studies. Factors were identified using an inductive thematic approach and mapped to the Theoretical Domains Framework (TDF). Comparisons between dental and other settings were explored. Registration number: PROSPERO_CRD42016037174.
resultsSearches identified 689 publications across primary care and 432 across dental care. Included studies (nine and seven, respectively) were assessed as of variable quality. They covered 46 countries, of which 12 were low and middle-income countries (LMICs). Across the two reviews, 30 factors were identified, with 'patient/condition characteristics', 'patient influence' and 'guidelines & information' the most frequent. Two factors were unique to dental studies: 'procedure possible' and 'treatment skills'. No factor related only to LMICs.
conclusionsA comprehensive list of factors associated with antibiotic prescribing to adults with acute conditions in primary care settings around the world has been collated and should assist theory-informed design of new context-specific stewardship interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.