ArticleEmerging infectious diseases2019
Recurrent Cholera Outbreaks, Democratic Republic of the Congo, 2008-2017.
Article in Emerging infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis.PLoS medicine · 2023Pooled it
- Long-Term Kinetics of Serological Antibodies againstInternational journal of environmental research and public health · 2022Pooled it
- Effect of a Water, Sanitation, and Hygiene Program on Handwashing with a Cleansing Agent among Diarrhea Patients and Attendants in Healthcare Facilities in the Democratic Republic of the Congo: A Randomized Pilot of the PICHA7 Program.International journal of environmental research and public health · 2024Trial
- A Phase 2a randomized, single-center, double-blind, placebo-controlled study to evaluate the safety and preliminary efficacy of oral iOWH032 against cholera diarrhea in a controlled human infection model.PLoS neglected tropical diseases · 2021Trial
- Cluster analysis of the spatial distribution of cholera in Uganda.BMC infectious diseases · 2026Article
- Epidemiologic Characteristics and Predictors of Mortality in Somalia's 2024 Cholera Outbreak.Journal of epidemiology and global health · 2026Article
- The westward spread dynamics of cholera from the eastern endemic Democratic Republic of the Congo.Emerging microbes & infections · 2025Article
- Providing spatial support during a major cholera outbreak in Port-au-Prince, Haiti: Creative mapping solutions in a challenging data poor environment.Spatial and spatio-temporal epidemiology · 2025Article
- A simulation-based policy analysis of anticipatory action for cholera outbreaks, Democratic Republic of the Congo.Bulletin of the World Health Organization · 2025Article
- Risk factors for cholera mortality: A scoping review.Tropical medicine & international health : TM & IH · 2025Article
- Cholera in conflict: outbreak analysis and response lessons from Gadaref state, Sudan (2023-2024).BMC public health · 2025Article
- Article
- Vibrio cholerae: Understanding a persistent pathogen in Sub-Saharan Africa and the East Mediterranean Region.Pathogens and disease · 2025Review
- Assessment of Management Factors Influencing Vaccination Against Cholera in the Health District of Katana, the Democratic Republic of the Congo.Health services insights · 2025Article
- Facility capacity and provider knowledge for cholera surveillance and diarrhoea case management in cholera hotspots in the Democratic Republic of Congo - a mixed-methods study.Global health action · 2024Article
- Genomic evolution and rearrangement of CTX-Φ prophage elements inEmerging microbes & infections · 2024Article
- Spatiotemporal Modeling of Cholera, Uvira, Democratic Republic of the Congo, 2016-2020.Emerging infectious diseases · 2024Article
- Spatiotemporal dynamics of cholera hotspots in the Democratic Republic of the Congo from 1973 to 2022.BMC infectious diseases · 2024Review
- Cholera Deaths During Outbreaks in Uvira, Eastern Democratic Republic of the Congo, 10-35 Months After Mass Vaccination.Open forum infectious diseases · 2024Article
- Syndemic Challenges: Addressing the Resurgence of Mpox Amidst Concurrent Outbreaks in the DRC.Transboundary and emerging diseases · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2017, the exacerbation of an ongoing countrywide cholera outbreak in the Democratic Republic of the Congo resulted in >53,000 reported cases and 1,145 deaths. To guide control measures, we analyzed the characteristics of cholera epidemiology in DRC on the basis of surveillance and cholera treatment center data for 2008-2017. The 2017 nationwide outbreak resulted from 3 distinct mechanisms: considerable increases in the number of cases in cholera-endemic areas, so-called hot spots, around the Great Lakes in eastern DRC; recurrent outbreaks progressing downstream along the Congo River; and spread along Congo River branches to areas that had been cholera-free for more than a decade. Case-fatality rates were higher in nonendemic areas and in the early phases of the outbreaks, possibly reflecting low levels of immunity and less appropriate prevention and treatment. Targeted use of oral cholera vaccine, soon after initial cases are diagnosed, could contribute to lower case-fatality rates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.