Evidence map›Paper›PMID 31002071›Full record

ArticleEmerging infectious diseases2019

Serologic Prevalence of Ebola Virus in Equatorial Africa.

Imke Steffen, Kai Lu, Lauren K Yamamoto, Nicole A Hoff, Prime Mulembakani, Emile O Wemakoy, Jean-Jacques Muyembe-Tamfum, Nicaise Ndembi, Catherine A Brennan, John Hackett and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Pseudotyped Viruses for Marburgvirus and Ebolavirus.Advances in experimental medicine and biology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Imke Steffen
Kai Lu
Lauren K Yamamoto
Nicole A Hoff
Prime Mulembakani
Emile O Wemakoy
Jean-Jacques Muyembe-Tamfum
Nicaise Ndembi
Catherine A Brennan
John Hackett
Susan L Stramer
William M Switzer
Sentob Saragosti
Guy O Mbensa
Syria Laperche
Anne W Rimoin
Graham Simmons

Funding

Serological prevalence of viral hemorrhagic fevers in Equatorial AfricaR21AI107420 · NIAID · VITALANT · PI SIMMONS, GRAHAM · 2014 to 2015
$438k
NIAID NIH HHS R21 AI107420
6 · The paper itself

Abstract

We conducted a serologic survey of 2,430 serum samples collected during 1997-2012 for various studies to determine the prevalence of the hemorrhagic fever virus Ebola virus (EBOV) in equatorial Africa. We screened serum samples for neutralizing antibodies by using a pseudotype microneutralization assay and a newly developed luciferase immunoprecipitation system assay. Specimens seroreactive for EBOV were confirmed by using an ELISA. Our results suggest a serologic prevalence of 2%-3.5% in the Republic of the Congo and the Democratic Republic of the Congo, which have reported outbreaks of infection with EBOV. In addition we detected a seroprevalence of 1.3% in southern Cameroon, which indicated a low risk for exposure in this region.

Indexed as

EbolavirusAfrica, CentralAntibodies, ViralEnzyme-Linked Immunosorbent AssayHEK293 CellsHemorrhagic Fever, EbolaHumansImmunoprecipitationNucleoproteinsSeroepidemiologic StudiesViral Core ProteinsViral Envelope ProteinsAntibodies, Viralenvelope glycoprotein, Ebola virusNucleoproteinsnucleoprotein VP40, Ebola virusViral Core ProteinsViral Envelope ProteinsCameroonDemocratic Republic of the CongoEbola virusELISAequatorial AfricafilovirusGhanahemorrhagic feverhemorrhagic fever virusluciferase immunoprecipitation systemneutralization assaypseudotypesRepublic of the Congoserologic prevalenceUgandaviruses

Identifiers

PMID31002071
PMCPMC6478206
OpenAlexW2921240776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.