Evidence map›Paper›PMID 31002019›Full record

ReviewCancer biology & therapy2019

Pancreatic acinar cell carcinoma is associated with

Valentyna Kryklyva, Nadia Haj Mohammad, Folkert H M Morsink, Marjolijn J L Ligtenberg, G Johan A Offerhaus, Iris D Nagtegaal, Wendy W J de Leng, Lodewijk A A Brosens

Open access · hybridAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer biology & therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Metastatic pancreatic acinar cell carcinoma withJournal of gastrointestinal oncology · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Genomic Profiling Reveals Germline Predisposition and Homologous Recombination Deficiency in Pancreatic Acinar Cell Carcinoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Pancreatic acinar cell carcinoma: A comprehensive review.World journal of gastroenterology · 2022
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. RET gene rearrangements occur in a subset of pancreatic acinar cell carcinomas.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Valentyna Kryklyvaa Department of Pathology , Radboud Institute for Molecular Life Sciences, Radboud university medical center , Nijmegen , The Netherlands.
Nadia Haj Mohammadb Department of Medical Oncology , University Medical Center Utrecht, Utrecht University , Utrecht , The Netherlands.
Folkert H M Morsinkc Department of Pathology , University Medical Center Utrecht, Utrecht University , Utrecht , The Netherlands.
Marjolijn J L Ligtenberga Department of Pathology , Radboud Institute for Molecular Life Sciences, Radboud university medical center , Nijmegen , The Netherlands.
G Johan A Offerhausc Department of Pathology , University Medical Center Utrecht, Utrecht University , Utrecht , The Netherlands.
Iris D Nagtegaala Department of Pathology , Radboud Institute for Molecular Life Sciences, Radboud university medical center , Nijmegen , The Netherlands.
Wendy W J de Lengc Department of Pathology , University Medical Center Utrecht, Utrecht University , Utrecht , The Netherlands.
Lodewijk A A Brosensa Department of Pathology , Radboud Institute for Molecular Life Sciences, Radboud university medical center , Nijmegen , The Netherlands.
Radboud University Medical Center · NLUniversity Medical Center Utrecht · NLUtrecht University · NLRadboud Institute for Molecular Life Sciences · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acinar cell carcinoma (ACC) is a rare pancreatic neoplasm with dismal prognosis. Insights into the molecular basis of ACC can pave the way for the application of more effective, personalized therapies and detection of patients with hereditary predisposition. Molecular analysis revealed a germline

Indexed as

Genetic Predisposition to DiseaseGerm-Line MutationBiomarkers, TumorBiopsyBRCA1 ProteinBRCA2 ProteinCarcinoma, Acinar CellDisease ManagementGenetic Association StudiesGenetic TestingHumansImmunohistochemistryMaleMiddle AgedNucleic Acid Amplification TechniquesPancreatic NeoplasmsBiomarkers, TumorBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanAcinar cell carcinoma of the pancreasgermline mutationsomatic mutation

Identifiers

PMID31002019
PMCPMC6606020
OpenAlexW2937345108

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.