Evidence map›Paper›PMID 31001930›Full record

ArticleFEBS open bio2019

Epigenetic regulation of regulatory T cells in patients with abdominal aortic aneurysm.

Qian Xia, Jian Zhang, Yanshuo Han, Xiaoyu Zhang, Han Jiang, Yu Lun, Xiaoyu Wu, Qingwei Gang, Zhimin Liu, Dittmar Böckler and 2 more

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Novel pharmacological approaches in abdominal aortic aneurysm.Clinical science (London, England : 1979) · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Qian XiaDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Jian ZhangDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Yanshuo HanDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Xiaoyu ZhangDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Han JiangDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Yu LunDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Xiaoyu WuDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Qingwei GangDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Zhimin LiuDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Dittmar BöcklerDepartment of Vascular and Endovascular Surgery, University of Heidelberg, Heidelberg, Germany.
Zhiquan DuanDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
Shijie XinDepartment of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China.
China Medical University · CNFirst Hospital of China Medical University · CNHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal arterial aneurysm (AAA) shares many features with autoimmune diseases and appears to be a T-cell-mediated process. In addition, certain epigenetic changes, including DNA methylation, are associated with AAA. In this study, we investigated epigenetic modifications in regulatory T cells (Tregs) from AAA patients. We used flow cytometry to sort FOXP3

Indexed as

AcetylationAgedAortic Aneurysm, AbdominalDNA-Binding ProteinsDNA (Cytosine-5-)-Methyltransferase 1DNA (Cytosine-5-)-MethyltransferasesDNA MethylationDNA Methyltransferase 3AEndodeoxyribonucleasesEpigenesis, GeneticFemaleHistone Deacetylase 1Histone DeacetylasesHistonesHumansMaleDNA-Binding ProteinsDNA (Cytosine-5-)-Methyltransferase 1DNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT1 protein, humanDNMT3A protein, humanEndodeoxyribonucleasesHDAC1 protein, humanHDAC5 protein, humanHistone Deacetylase 1Histone DeacetylasesHistonesMBD2 protein, humanMBD4 protein, humanRNA, Messengerabdominal aortic aneurysmDNA methylationepigeneticshistone modificationsregulatory T cells

Identifiers

PMID31001930
PMCPMC6551495
OpenAlexW2936127776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.