Evidence map›Paper›PMID 31001752›Full record

ArticleJournal of the American Society for Mass Spectrometry2019

Ultra-High Resolution Elemental/Isotopic Mass Spectrometry (m/Δm > 1,000,000): Coupling of the Liquid Sampling-Atmospheric Pressure Glow Discharge with an Orbitrap Mass Spectrometer for Applications in Biological Chemistry and Environmental Analysis.

Edward D Hoegg, Simon Godin, Joanna Szpunar, Ryszard Lobinski, David W Koppenaal, R Kenneth Marcus

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Edward D HoeggDepartment of Chemistry, Clemson University, Clemson, SC, 29634, USA.
Simon GodinCNRS, Institute for Analytical & Physical Chemistry of the Environment & Materials, UPPA, IPREM, UMR 5254, Helioparc 2, Av Pr Angot, F-64053, Pau, France.
Joanna SzpunarCNRS, Institute for Analytical & Physical Chemistry of the Environment & Materials, UPPA, IPREM, UMR 5254, Helioparc 2, Av Pr Angot, F-64053, Pau, France.
Ryszard LobinskiCNRS, Institute for Analytical & Physical Chemistry of the Environment & Materials, UPPA, IPREM, UMR 5254, Helioparc 2, Av Pr Angot, F-64053, Pau, France.
David W KoppenaalPacific Northwest National Laboratory, EMSL, 902 Battelle Blvd, Richland, WA, 99354, USA.
R Kenneth MarcusDepartment of Chemistry, Clemson University, Clemson, SC, 29634, USA. MarcusR@Clemson.Edu.ORCID http://orcid.org/0000-0003-4276-5805
Clemson University · USInstitut des Sciences Analytiques et de Physico-Chimie pour l'Environnement et les Matériaux · FRBattelle · USCentre National de la Recherche Scientifique · FR

Funding

Agence de l'Environnement et de la Maîtrise de l'Energie NAAgence Nationale de la Recherche MARSS ANR 11-EQPX-0027Defense Threat Reduction Agency #HDTRA1-14-1-0010
6 · The paper itself

Abstract

Many fundamental questions of astrophysics, biochemistry, and geology rely on the ability to accurately and precisely measure the mass and abundance of isotopes. Taken a step further, the capacity to perform such measurements on intact molecules provides insights into processes in diverse biological systems. Described here is the coupling of a combined atomic and molecular (CAM) ionization source, the liquid sampling-atmospheric pressure glow discharge (LS-APGD) microplasma, with a commercially available ThermoScientific Fusion Lumos mass spectrometer. Demonstrated for the first time is the ionization and isotopically resolved fingerprinting of a long-postulated, but never mass-spectrometrically observed, bi-metallic complex Hg:Se-cysteine. Such a complex has been implicated as having a role in observations of Hg detoxification by selenoproteins/amino acids. Demonstrated as well is the ability to mass spectrometrically-resolve the geochronologically important isobaric

Indexed as

AnimalsAtmospheric PressureEnvironmental MonitoringEquipment DesignFlow Injection AnalysisHumansIsotopesMass SpectrometryMercurySelenocysteineSelenoproteinsIsotopesMercurySelenocysteineSelenoproteinsHigh resolutionIsotope analysisMercury:selenoamino acidMetallobiochemistryMicroplasmaOrbitrap

Identifiers

PMID31001752
OpenAlexW2939740113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.