Evidence map›Paper›PMID 31001720›Full record

ArticleJournal of the Association for Research in Otolaryngology : JARO2019

Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.

Antje K Huebner, Hannes Maier, Alena Maul, Sandor Nietzsche, Tanja Herrmann, Jeppe Praetorius, Christian A Hübner

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Association for Research in Otolaryngology : JARO, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. A Systematic Review of Genes Affecting Endocochlear Potential.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Pooled it
  2. Review
  3. Review
  4. Biallelic variants in SLC4A10 encoding a sodium-dependent bicarbonate transporter lead to a neurodevelopmental disorder.Genetics in medicine : official journal of the American College of Medical Genetics · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. The therapeutic importance of acid-base balance.Biochemical pharmacology · 2021
    Review
  13. Article
  14. Article
  15. Noncoding Microdeletion in MouseThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Antje K HuebnerInstitute of Human Genetics, Jena University Hospital, Friedrich Schiller Universität, Am Klinikum 1, 07747, Jena, Germany.
Hannes MaierDepartment of Otolaryngology and Cluster of Excellence Hearing4all, Deutsches HörZentrum Hannover, Medical University Hannover, Karl-Wiechert-Allee 3, 30625, Hannover, Germany.
Alena MaulMax-Delbrück Centrum für Molekulare Medizin (MDC) and NeuroCure, Robert-Rössle-Str. 10, 13092, Berlin, Germany.
Sandor NietzscheElectron Microscopy Center, Jena University Hospital, Friedrich Schiller Universität, Ziegelmühlenweg 1, 07743, Jena, Germany.
Tanja HerrmannInstitute of Human Genetics, Jena University Hospital, Friedrich Schiller Universität, Am Klinikum 1, 07747, Jena, Germany.
Jeppe PraetoriusDepartment of Biomedicine, Health, Aarhus University, Aarhus, Denmark.
Christian A HübnerInstitute of Human Genetics, Jena University Hospital, Friedrich Schiller Universität, Am Klinikum 1, 07747, Jena, Germany. Christian.huebner@med.uni-jena.de.
Friedrich Schiller University Jena · DEAarhus University · DKHearing4all · DEJena University Hospital · DEMax Delbrück Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unique composition of the endolymph with a high extracellular K

Indexed as

AnimalsChloride-Bicarbonate AntiportersConnexin 26Connexin 30ConnexinsHearingMice, Inbred C57BLMice, KnockoutMitochondriaSodium-Bicarbonate SymportersSpiral Ligament of CochleaChloride-Bicarbonate AntiportersConnexin 26Connexin 30ConnexinsGjb2 protein, mouseGjb6 protein, mouseSlc4a10 protein, mouseSlc4a7 protein, mouseSodium-Bicarbonate Symportersbicarbonate transportdeafnessfibrocyteNCBEpHSlc4a10Slc4a7

Identifiers

PMID31001720
PMCPMC6514043
OpenAlexW2936098322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.